What is the Apnea-Hypopnea Index (AHI) for a patient with 10 episodes of apnea and 25 episodes of hypopnea over 6 hours of sleep?

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AHI Calculation

The AHI for this patient is 5.8 events per hour, calculated by dividing the total number of respiratory events (35) by the total sleep time in hours (6), which classifies as mild obstructive sleep apnea. 1

Calculation Method

The Apnea-Hypopnea Index (AHI) is defined as the sum of apneas and hypopneas per hour of sleep. 1

For this patient:

  • Total apnea episodes: 10 1
  • Total hypopnea episodes: 25 1
  • Total respiratory events: 35 1
  • Total sleep time: 6 hours 1
  • AHI = 35 events ÷ 6 hours = 5.8 events/hour 1

Severity Classification

According to the American Academy of Sleep Medicine criteria, this AHI of 5.8 falls into the mild OSA category (AHI 5-14 events/hour). 2

The standardized severity thresholds are: 3, 2

  • Normal: AHI 0-5 events/hour
  • Mild OSA: AHI 5-14 events/hour (this patient)
  • Moderate OSA: AHI 15-29 events/hour
  • Severe OSA: AHI ≥30 events/hour

Important Clinical Caveats

The AHI alone may not fully capture the physiological stress of sleep-disordered breathing, as it does not account for the duration or morphology of individual respiratory events. 4, 5, 6 Patients with similar AHI values can exhibit significantly different cardiovascular stress related to their disease, with correlation between AHI and obstruction severity parameters showing only moderate agreement (r²=0.604). 4

Longer duration apnea and hypopnea events lead to deeper oxygen desaturations and greater physiological stress, yet paradoxically may result in a lower AHI if events are prolonged enough to reduce their frequency per hour. 4, 5 This means two patients with identical AHI values of 5.8 could have vastly different clinical severity depending on whether their events last 10-15 seconds versus 30-40 seconds. 4, 6

The definition of hypopnea significantly impacts AHI calculation, with the American Academy of Sleep Medicine defining hypopnea as a ≥30% reduction in airflow for ≥10 seconds associated with either ≥3% oxygen desaturation or an arousal. 2 Some respiratory limitations lasting 5-10 seconds with associated desaturation may be clinically significant but excluded from standard AHI calculations. 7

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Diagnostic Thresholds for Sleep Apnea

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Severe Obstructive Sleep Apnea Management

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Which is more important: the number or duration of respiratory events to determine the severity of obstructive sleep apnea?

The aging male : the official journal of the International Society for the Study of the Aging Male, 2020

Research

Evaluation of an alternative definition for the apnea-hypopnea index.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference, 2010

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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