What is the appropriate management for a patient suspected of having Nipah virus infection, presenting with symptoms such as fever, headache, and respiratory distress, and a history of exposure to potentially infected animals or people?

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Last updated: January 30, 2026View editorial policy

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Given the potential severity of Nipah virus infection, it is crucial to approach any suspected case with caution. If a patient is suspected of having Nipah virus infection, based on symptoms such as fever, headache, and respiratory distress, and a history of exposure to potentially infected animals or people, immediate isolation and supportive care are recommended. The patient should be placed in a negative pressure isolation room, and healthcare workers should use personal protective equipment (PPE) to minimize the risk of transmission. There is no specific antiviral treatment approved for Nipah virus infection, but ribavirin has been used in some cases. The dose of ribavirin can vary, but it is typically administered intravenously at a dose of 30 mg/kg loading dose, followed by 15 mg/kg every 6 hours for 4 days, then 7.5 mg/kg every 8 hours for 3 days. Second-line interventions may include management of complications such as seizures, which can be treated with medications like phenytoin or valproate. It's also essential to monitor the patient's respiratory status closely and provide mechanical ventilation if necessary. Given the high risk of morbidity and mortality associated with Nipah virus infection, any patient with suspected or confirmed infection should be managed in an intensive care unit with access to advanced life support measures.

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This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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