What is the medical term for a mass in a man's testicle?

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Medical Terminology for Testicular Mass

A mass in a man's testicle is most commonly called a testicular mass or testicular tumor in medical terminology, with the specific diagnosis depending on whether it is intratesticular (inside the testis) or extratesticular (outside the testis). 1, 2

Key Clinical Distinctions

The critical first determination is whether the mass is intratesticular or extratesticular, as approximately 90% of intratesticular masses are malignant, while extratesticular masses are usually benign. 3, 4

Intratesticular Masses

  • Germ cell tumors (GCTs) represent 90-95% of testicular cancers and are divided into two main types: 5

    • Seminoma - accounts for approximately 40-50% of testicular GCTs 1, 6
    • Non-seminomatous germ cell tumors (NSGCTs) - accounts for the remaining 50% 1
  • The term testicular germ cell cancer (TGCC) is used when referring to malignant germ cell tumors specifically 1

  • Less common intratesticular masses include lymphoma, sex cord-stromal tumors, and metastases 7

Extratesticular Masses (Usually Benign)

  • Epididymal cysts (or spermatoceles when containing sperm) - the most common finding in scrotal lumps, accounting for 27% of cases 4

  • Hydrocele - fluid collection between layers of the tunica vaginalis, found in 11% of cases 4

Clinical Presentation

  • The most common presenting symptom is a painless testicular mass, though some patients may present with pain 5, 7

  • Testicular cancer primarily affects Caucasian males aged 15-40 years, with a mean age at diagnosis of 33 years 1, 5

Diagnostic Terminology

  • Testicular sonography or scrotal ultrasound is the mandatory first-line imaging study to characterize any testicular mass 1, 2, 3

  • The definitive diagnosis requires radical inguinal orchiectomy, which provides histological confirmation 1, 6, 2

Important Clinical Caveat

Any solid mass within the testis should be managed as malignant until proven otherwise, requiring urgent scrotal ultrasound and serum tumor markers (AFP, β-HCG, LDH) before any intervention. 3 The high malignancy rate of intratesticular masses (90%) makes this assumption critical for appropriate management. 3, 4

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Diagnostic Approach and Management of Painful Testicular Mass

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Diagnostic Approach and Management of Scrotal Lumps

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Diagnosing testicular lumps in primary care.

The Practitioner, 2017

Guideline

Seminoma Diagnosis and Treatment

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Testicular Seminoma and Its Mimics: From the Radiologic Pathology Archives.

Radiographics : a review publication of the Radiological Society of North America, Inc, 2017

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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