What is the ICD-10 (International Classification of Diseases, 10th Revision) code for an asymptomatic adult patient undergoing Fecal Occult Blood Test (FOBT) screening for colorectal cancer?

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Last updated: January 30, 2026View editorial policy

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ICD-10 Code for FOBT Screening

For asymptomatic adults undergoing routine FOBT screening for colorectal cancer, use ICD-10 code Z12.11 (Encounter for screening for malignant neoplasm of colon).

Primary Screening Code

  • Z12.11 is the appropriate ICD-10 code for colorectal cancer screening encounters in asymptomatic average-risk adults aged 50 and older undergoing FOBT 1, 2

  • This code applies when the patient has no signs, symptoms, or personal history of colorectal cancer and is presenting specifically for preventive screening 1

Clinical Context for Proper Coding

Age-appropriate screening parameters:

  • Standard screening begins at age 50 for average-risk individuals and continues through age 75 1, 2

  • Annual FOBT is the recommended screening interval for both guaiac-based (gFOBT) and fecal immunochemical tests (FIT) 1, 2

  • For ages 76-85, screening decisions should be individualized based on prior screening history and life expectancy, but Z12.11 remains appropriate when screening is performed 1

Important coding distinctions:

  • Z12.11 should only be used for true screening in asymptomatic patients 1

  • If the patient has gastrointestinal symptoms (bleeding, anemia, abdominal pain, change in bowel habits), this is diagnostic testing, not screening, and symptom-specific codes should be used instead 3

  • Single-sample FOBT obtained during digital rectal examination in the office should not be coded as screening because it is not an acceptable screening test with sensitivity of only 4.9% for advanced neoplasia 4

Follow-up Coding Considerations

When FOBT is positive:

  • The follow-up colonoscopy should be coded as diagnostic (not screening) because it is investigating an abnormal finding 4

  • Any positive FOBT requires colonoscopy within 60 days; repeating the FOBT is inappropriate 2, 4

  • Approximately 10% of positive FOBTs will reveal colorectal cancer and 37% will show adenomatous polyps on subsequent colonoscopy 5

Critical implementation requirements:

  • Home-based specimen collection with 3 stool samples is required for proper FOBT screening 4

  • High-sensitivity gFOBT (such as Hemoccult SENSA) should be used rather than older, lower-sensitivity versions 1, 2

  • Patients must understand that annual testing is necessary to achieve the mortality reduction benefit of FOBT screening 1, 2

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

FOBT Screening Frequency for Colorectal Cancer

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2026

Guideline

Next Step After Positive Fecal Occult Blood Test (FOBT)

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2026

Guideline

Probability of Positive FOBT in Asymptomatic Individuals for Colorectal Cancer

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2026

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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