Management of Bronchitis
Distinguish Between Acute and Chronic Bronchitis First
The most critical initial step is determining whether you are managing acute bronchitis (self-limited viral illness) or chronic bronchitis (chronic inflammatory condition), as their management differs fundamentally. 1, 2
Acute Bronchitis
- Defined as acute cough lasting up to 6 weeks due to self-limited inflammation of large airways, typically without fever or significant systemic symptoms 2, 3
- More than 90% of cases are viral; antibiotics provide minimal benefit (reducing cough by only 0.5 days) while exposing patients to adverse effects 2, 4, 3
- Do NOT prescribe antibiotics for uncomplicated acute bronchitis 1, 2, 3
Chronic Bronchitis
- Defined as cough with sputum production on most days for at least 3 months per year for 2 consecutive years 5, 1
- Requires long-term management focused on bronchodilation, smoking cessation, and preventing exacerbations 5, 1
Management of Acute Bronchitis
Rule Out Pneumonia First
Before diagnosing uncomplicated acute bronchitis, assess for tachycardia, tachypnea, fever, and abnormal chest examination findings to rule out pneumonia. 1, 6 Normal vital signs in healthy adults under 70 years effectively rules out pneumonia 2.
Antibiotic Use: Almost Never Indicated
- Antibiotics should NOT be prescribed for acute bronchitis 1, 2, 3
- Consider antibiotics ONLY in these specific high-risk situations:
Symptomatic Management
- Short-acting β-agonists (albuterol) may reduce cough duration and severity in patients with evidence of bronchial hyperresponsiveness 1
- Ipratropium bromide may improve cough in some patients 1
- Dextromethorphan or codeine for short-term symptomatic relief of bothersome cough 1
- Do NOT use antitussives, honey, antihistamines, oral NSAIDs, or inhaled/oral corticosteroids—evidence does not support their use 3
Patient Communication Strategy
The quality of your clinical encounter matters more than prescribing antibiotics for patient satisfaction. 1
- Set realistic expectations: cough typically lasts 10-14 days after the visit, sometimes up to 3 weeks 1, 3, 6
- Call it a "chest cold" rather than "bronchitis" to reduce patient expectation for antibiotics 1, 3, 6
- Explain that colored (green/yellow) sputum does NOT indicate bacterial infection—it results from inflammatory cells or sloughed epithelial cells 1, 4
- Discuss risks of unnecessary antibiotics: side effects, allergic reactions, Clostridium difficile infection, and antibiotic resistance 1, 6
Management of Chronic Bronchitis
Smoking Cessation: The Most Effective Intervention
Smoking cessation is the single most effective intervention for chronic bronchitis, with 90% of patients experiencing cough resolution after quitting. 5, 1 Remove all respiratory irritants including passive smoke exposure and workplace/environmental hazards 5, 1.
Stable Chronic Bronchitis: Bronchodilator Therapy
Short-acting β-agonists should be used to control bronchospasm, relieve dyspnea, and may reduce chronic cough. 5, 1
- Ipratropium bromide should be offered to improve cough and reduce sputum volume 5, 1
- Theophylline may be considered to control chronic cough, but requires careful monitoring for complications 5
Advanced Therapy for Severe Disease
- Long-acting β-agonists combined with inhaled corticosteroids should be offered to control chronic cough and reduce exacerbation rates 1
- Inhaled corticosteroids are recommended when FEV1 <50% predicted or with frequent exacerbations 5, 1
What NOT to Use
- Do NOT use long-term prophylactic antibiotics in stable chronic bronchitis 5
- Do NOT use long-term oral corticosteroids—no evidence of benefit and high risk of side effects 5, 1
- Do NOT use expectorants or mucolytics—no evidence of benefit 5, 1
- Do NOT use postural drainage or chest percussion—not proven effective 5
Management of Acute Exacerbations of Chronic Bronchitis
Immediate Bronchodilator Therapy
Administer short-acting β-agonists or anticholinergic bronchodilators immediately during acute exacerbations. 5, 1 If no prompt response, add the other agent after maximizing the first 5.
Antibiotic Use in Exacerbations
Antibiotics are recommended for acute exacerbations, especially in patients with severe exacerbations and baseline FEV1 <50%. 5, 1 Patients most likely to benefit include those with:
- Severe airflow obstruction at baseline 5
- Increased cough, sputum production, and sputum purulence 5
- Shortness of breath preceded by upper respiratory infection symptoms 5
Systemic Corticosteroids
A short course (10-15 days) of systemic corticosteroids should be given for acute exacerbations—both IV therapy for hospitalized patients and oral therapy for ambulatory patients are effective. 5, 1
What NOT to Use During Exacerbations
- Do NOT use theophylline for acute exacerbations 5, 1
- Do NOT use expectorants or mucolytics during exacerbations 5, 1
- Do NOT use postural drainage or chest percussion 5
Common Pitfalls to Avoid
- Do NOT prescribe antibiotics based solely on colored sputum—purulence does not indicate bacterial infection 1, 4
- Do NOT fail to distinguish acute bronchitis from pneumonia—check vital signs and lung examination 1, 6
- Do NOT overuse expectorants, mucolytics, and antihistamines—they lack evidence of benefit 1, 3
- Do NOT ignore underlying conditions (asthma, COPD, cardiac failure, diabetes) that may be exacerbated by bronchitis 1
- Consider delayed antibiotic prescriptions as a strategy to reduce inappropriate prescribing while maintaining patient satisfaction 3, 6