What is the typical appearance of eczema (atopic dermatitis) on the skin?

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Appearance of Eczema (Atopic Dermatitis)

Eczema presents as erythematous (red), pruritic (itchy) skin lesions with a characteristic age-specific distribution pattern, accompanied by xerosis (dry skin), and varying morphology depending on whether the lesions are acute, subacute, or chronic. 1, 2

Key Clinical Features by Lesion Stage

Acute Lesions

  • Erythematous papules with serous exudates (oozing) 1, 3
  • Edema (swelling) of affected areas 1
  • Erosions and excoriations from scratching 1, 3
  • Crusting when secondary bacterial infection is present 1, 2
  • Grouped, punched-out erosions or vesiculation suggest herpes simplex superinfection 1

Subacute Lesions

  • Erythematous scaling papules and plaques 3
  • Less oozing than acute lesions but persistent redness 3

Chronic Lesions

  • Lichenification (thickened skin with accentuated skin markings) 1, 3
  • Hyperpigmentation in affected areas 3
  • Persistent xerosis (dry skin) 1, 2

Age-Specific Distribution Patterns

Infants and Young Children (Under 4 Years)

  • Cheeks and forehead are commonly affected 1, 3
  • Scalp involvement 3
  • Outer limbs (extensor surfaces) 1
  • Notably spares the diaper area in infants 3

Older Children and Adults

  • Flexural areas are predominantly affected 1, 3
  • Antecubital fossae (inner elbows) 3
  • Popliteal fossae (behind knees) 3
  • Neck region 1, 3
  • Skin creases and folds 1

Universal Features Across All Ages

  • Symmetrical distribution of lesions 2
  • Xerosis (generalized dry skin) is present even in unaffected areas 1, 2
  • Intense pruritus is the hallmark symptom, often described as "the itch that rashes" 2, 4

Common Pitfalls in Recognition

Bacterial superinfection should be suspected when you observe weeping, crusting, or sudden worsening of previously stable eczema 1, 2. Staphylococcus aureus is the most common culprit 2, 3.

Eczema herpeticum (herpes simplex superinfection) presents with grouped, punched-out erosions or discrete vesicles and can be life-threatening, requiring immediate recognition 1, 3.

Contact dermatitis may develop as a complication and should be considered when previously controlled eczema suddenly deteriorates 1, 2.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Atopic Dermatitis Management and Pathophysiology

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Chapter 20: Atopic dermatitis.

Allergy and asthma proceedings, 2012

Research

Clinical Presentation of Atopic Dermatitis.

Advances in experimental medicine and biology, 2017

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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