What is the likely diagnosis and treatment for a 5-year-old child with an itchy, crusty rash on the face?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: February 3, 2026View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Itchy Crusty Rash on Face in a 5-Year-Old

The most likely diagnosis is atopic dermatitis (eczema) with secondary bacterial infection (impetigo), and treatment should include liberal emollients, mild topical corticosteroids (hydrocortisone 1% applied 3-4 times daily to the face), and oral antibiotics if crusting suggests bacterial superinfection. 1, 2, 3

Diagnosis

The clinical presentation strongly suggests atopic dermatitis affecting the face, which is the characteristic distribution in children under 5 years old. 4, 1 The diagnosis is clinical and requires an itchy skin condition plus three or more of the following: 4, 1

  • History of itchiness in skin creases (or cheeks/forehead in children under 4 years)
  • Personal or family history of asthma, hay fever, or atopic disease
  • General dry skin in the past year
  • Visible eczema on cheeks or forehead in young children
  • Onset in the first two years of life

The "crusty" component is critical - this suggests secondary bacterial infection (impetigo), which commonly complicates atopic dermatitis. 4, 3 Crusting, weeping, or honey-colored discharge indicates Staphylococcus aureus or Streptococcus pyogenes superinfection. 4, 3

Critical Red Flag to Rule Out

Examine carefully for eczema herpeticum - look for multiple uniform "punched-out" erosions or vesiculopustular eruptions that are very similar in shape and size. 2 This is a medical emergency requiring immediate systemic acyclovir. 1, 2 If suspected, send swabs for viral culture and electron microscopy. 4

Treatment Algorithm

Step 1: Baseline Management for All Cases

Emollients are the foundation of treatment and should be applied liberally at least twice daily and as needed throughout the day. 1, 2, 5 Use gentle dispersible cream cleansers as soap substitutes and avoid harsh detergents. 1, 2

Step 2: Topical Corticosteroids for Inflammation

Hydrocortisone 1% (mild potency) applied to the affected facial area 3-4 times daily is first-line for facial involvement in children. 2, 6 This is safe for children 2 years and older when used appropriately. 6 The face requires mild potency steroids due to thinner skin and higher absorption risk. 4

Step 3: Address Secondary Bacterial Infection

If crusting is present, treat for bacterial superinfection. 4, 3 The options are:

  • Topical antibiotics (mupirocin or fusidic acid) for localized infection 3, 7
  • Oral antibiotics for extensive crusting: 3, 7
    • First-line: Flucloxacillin, cephalexin, or amoxicillin/clavulanate (covers both S. aureus and Streptococcus)
    • If MRSA suspected: Clindamycin or trimethoprim/sulfamethoxazole 3
    • Avoid penicillin V - it is seldom effective for impetigo 7

Send bacterial swabs for culture if infection is suspected to guide antibiotic selection. 4

Follow-Up and Escalation

Reassess in 1-2 weeks if no improvement with initial therapy. 1, 2 Refer to dermatology if: 1

  • Not responding to first-line management within 1-2 weeks
  • Suspected eczema herpeticum (urgent referral)
  • Extensive crusting or severe bacterial superinfection
  • Diagnosis remains uncertain

Parent Education Points

Demonstrate proper application technique for emollients and medications with written instructions. 4, 1 Explain that: 1, 5

  • Deterioration in previously stable eczema may indicate infection requiring prompt evaluation
  • Appropriate topical corticosteroid use is safe - address parental fears about steroids
  • Avoid irritants including scented products, harsh soaps, and fabric softeners
  • Even mild eczema can significantly impact sleep and quality of life, justifying active management 5

Common Pitfalls to Avoid

Do not delay treatment if bacterial infection is suspected - the crusting component requires prompt antibiotic therapy. 4, 3

Do not assume dietary restriction will help - it is of little or no benefit except in selected infants under professional supervision. 4, 5

Do not miss eczema herpeticum - this is a true dermatologic emergency that can be fatal if untreated. 1, 2

References

Guideline

Diagnosis and Management of Atopic Eczema in Children

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2026

Guideline

Differential Diagnosis and Management of Dry, Itchy, Red Cheeks

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Impetigo: diagnosis and treatment.

American family physician, 2014

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Atopic Eczema Management and Prognosis

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2026

Research

Diagnosis and treatment of impetigo.

American family physician, 2007

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.