What are the benefits and contraindications of Nigella sativa (Black seed) oil?

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Last updated: April 19, 2025View editorial policy

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From the Research

Black seed oil, derived from Nigella sativa, is recommended for its anti-inflammatory, antioxidant, and immune-boosting properties, but its use should be approached with caution due to potential interactions and contraindications, as evidenced by the most recent and highest quality study 1.

Benefits of Black Seed Oil

The benefits of black seed oil include:

  • Anti-inflammatory effects: reducing inflammation and oxidative stress in the body 1
  • Antioxidant effects: protecting against cell damage and reducing the risk of chronic diseases 1
  • Immune-boosting properties: supporting the immune system and reducing the risk of infections 2
  • Potential therapeutic effects: managing conditions like asthma, high blood pressure, and diabetes 3

Contraindications and Interactions

However, black seed oil also has important contraindications and interactions to consider:

  • Pregnancy: may stimulate uterine contractions and should be avoided 1
  • Bleeding disorders: may interact with medications that affect blood clotting and should be used with caution 1
  • Surgery: may interact with medications that affect blood clotting and should be avoided before surgery 1
  • Low blood pressure: may lower blood pressure and should be used with caution 1
  • Medications: may interact with medications that affect blood clotting or blood sugar levels and should be used under the guidance of a healthcare provider 1

Recommended Use

To use black seed oil safely and effectively:

  • Start with a small dose to test tolerance 1
  • Consult with a healthcare provider before using black seed oil, especially if you have existing health conditions or take medications 1
  • Use high-quality black seed oil that is standardized to contain a consistent amount of thymoquinone, the active compound responsible for its therapeutic effects 4

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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