What is the best treatment for a patient with a chalazion, possibly with a history of blepharitis or meibomian gland dysfunction?

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How to Treat a Bump on Your Eyelid (Chalazion)

Start with warm compresses and eyelid cleaning at home for 4-6 weeks—this works for most people and should be your first step. 1, 2

What You Need to Do at Home

Warm compresses (most important):

  • Apply a warm, wet washcloth to your closed eyelid for several minutes, 1-2 times every day 1
  • You can use hot tap water on a clean washcloth, a heat pack from the store, or a microwaveable rice/bean bag 1, 3
  • Make sure it's warm but not hot enough to burn your skin 1, 3
  • This helps melt the blocked oil and lets it drain out 1

Eyelid cleaning:

  • After the warm compress, gently massage your eyelid in an up-and-down motion to help push out the blocked oil 1, 3
  • Clean your eyelid margin using diluted baby shampoo or special eyelid wipes you can buy at the pharmacy 1, 3
  • Hypochlorous acid 0.01% cleaners (available over-the-counter) work especially well because they kill germs 1, 3
  • Do this every day 3

If you have crusty eyelids or a history of eyelid inflammation:

  • Your doctor may add an antibiotic ointment like bacitracin or erythromycin to rub on your eyelid margins 1, 3
  • This treats the underlying eyelid inflammation that may be causing your chalazion to keep coming back 1, 3

When Home Treatment Isn't Enough

If the bump doesn't go away after 4-6 weeks of doing everything above, you need to see your eye doctor for the next step. 2

Your doctor has two main options:

Option 1: Steroid injection

  • A small injection of medicine (triamcinolone) directly into the bump 4
  • Works about 84% of the time 4
  • Less painful than surgery and more convenient 4
  • Similar success rate to surgery 4

Option 2: Minor surgery

  • The doctor makes a small cut and scoops out the blocked material 2, 5
  • Works about 87% of the time 4
  • Usually done from the inside of your eyelid so there's no visible scar 5
  • More painful than the injection but still very effective 4

Important Warnings

See your doctor right away if:

  • The bump keeps coming back in the same spot 1
  • You're losing eyelashes where the bump is 1
  • The bump looks very different from your other eyelid 1
  • It doesn't respond to treatment 1, 6

These could be signs of eyelid cancer, which needs to be ruled out with a biopsy 1, 6

Special Situations

If you have ongoing eyelid inflammation (blepharitis):

  • You need to keep doing eyelid hygiene every day forever, not just until the bump goes away 3
  • This is a chronic condition that comes back if you stop treatment 3
  • Your doctor may prescribe oral antibiotics like doxycycline if your eyelid inflammation is severe 3

If you have glaucoma:

  • Don't press too hard on your eyelid during massage—this can increase eye pressure 1, 3

If your immune system is weak:

  • You may need antibiotics sooner and closer monitoring 1

What to Expect

  • Most chalazia resolve with home treatment if you're consistent 2
  • Conservative treatment alone (just warm compresses) only works about 46% of the time, which is why adding proper eyelid hygiene and sometimes antibiotics is important 4
  • If you need an injection or surgery, both work well—the injection is less painful and more convenient 4
  • These bumps can come back, so keep up with daily eyelid hygiene even after it's gone 1, 3

References

Guideline

Chalazion Treatment Guidelines

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2026

Guideline

Medical Necessity of Chalazion Drainage and Removal

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2026

Guideline

Treatment of Blepharitis

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2026

Research

Chalazion surgery: advantages of a subconjunctival approach.

Journal of cosmetic and laser therapy : official publication of the European Society for Laser Dermatology, 2009

Research

[Hordeolum and chalazion : (Differential) diagnosis and treatment].

Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft, 2022

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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