From the Research
Bremelanotide (brand name Vyleesi) typically costs between $900 to $1,000 per package, which contains four autoinjector pens, making the cost approximately $225 to $250 per dose. This medication is used to treat acquired, generalized hypoactive sexual desire disorder (HSDD) in premenopausal women 1. The cost of bremelanotide can be a significant factor in its accessibility, and insurance coverage varies significantly, with many plans not covering it or requiring prior authorization 2. Some patients may qualify for manufacturer savings programs that can reduce the cost to around $99 per package. Bremelanotide works by activating melanocortin receptors in the brain, which play a role in sexual function, as explained in a study on the neurobiology of bremelanotide for the treatment of HSDD in premenopausal women 3. The medication is self-administered as a subcutaneous injection into the abdomen or thigh approximately 45 minutes before anticipated sexual activity, with usage limited to one dose per 24 hours and no more than eight doses per month.
Key points to consider when prescribing bremelanotide include:
- The medication's efficacy in treating HSDD in premenopausal women, as demonstrated in clinical trials 4
- The potential side effects, such as nausea, flushing, and headache, which are mostly mild to moderate 4
- The importance of proper dosing and administration to minimize adverse effects 1
- The need for ongoing evaluation and monitoring of patients taking bremelanotide to ensure its safe and effective use 2
It is essential to weigh the benefits and costs of bremelanotide when making treatment decisions, considering the potential impact on patients' quality of life and sexual function. As noted in a study on the medical treatment of female sexual dysfunction, bremelanotide is one of the available options for treating HSDD in premenopausal women, and its cost should be taken into account when developing a treatment plan 2.