From the Research
Fevers from viral illnesses can range from 100.4°F (38°C) to 104°F (40°C), though they can occasionally reach 105°F (40.6°C) or slightly higher, especially in children, as supported by the most recent and highest quality study available 1. The management of fever in viral illnesses is crucial, and it is essential to consider the potential benefits and risks of antipyretic medications. According to a systematic review and meta-analysis published in 2021 1, there is no excess risk of SARS-CoV-2 positivity, hospital admission, death, or severe outcomes associated with the use of NSAIDs, including ibuprofen. Some key points to consider when managing fever in viral illnesses include:
- Staying hydrated by drinking plenty of fluids
- Resting as needed
- Using acetaminophen (Tylenol) at 325-650mg every 4-6 hours (not exceeding 3000mg daily) or ibuprofen (Advil, Motrin) at 200-400mg every 6-8 hours with food to help reduce fever, as suggested by a study published in 2020 2
- Seeking immediate medical attention for fevers above 103°F (39.4°C) that don't respond to medication, fevers lasting more than 3-5 days, or if accompanied by severe symptoms like difficulty breathing, extreme lethargy, confusion, stiff neck, or persistent vomiting. It is also important to note that fevers serve an important purpose in fighting infections by creating an environment less favorable for viral replication and enhancing immune function, as discussed in a study published in 2019 3. While the use of antipyretic medications can provide comfort, it is essential to weigh the potential benefits and risks, particularly in patients with underlying comorbidities or taking multiple medications, as highlighted in a study published in 2023 4.