Management of Acute Bronchitis in Adults
For an immunocompetent adult presenting with acute bronchitis (cough, low-grade fever, sputum production, no focal lung findings), no routine investigations or medications should be prescribed—this is a self-limiting viral illness requiring only patient education and symptomatic support. 1
Initial Clinical Assessment
The primary goal is to exclude pneumonia and other serious conditions before confirming acute bronchitis as the diagnosis. 1
Key vital signs and examination findings that suggest pneumonia (NOT bronchitis):
- Heart rate >100 beats/min 1
- Respiratory rate >24 breaths/min 1
- Oral temperature >38°C 1
- Focal lung findings on examination (rales, egophony, tactile fremitus) 2
If any of these are present, obtain chest radiography to evaluate for pneumonia rather than treating as simple bronchitis. 1, 2
Important differential diagnoses to consider:
- Asthma exacerbation or cough-variant asthma (approximately one-third of patients diagnosed with "acute bronchitis" actually have undiagnosed asthma) 1
- COPD exacerbation 1
- Pertussis (if cough persists >2 weeks with paroxysmal features, whooping, or post-tussive emesis) 3
- Bronchiectasis exacerbation 1
Diagnostic Testing: What NOT to Order
No routine investigations are recommended for uncomplicated acute bronchitis: 1
- No chest x-ray (unless vital signs abnormal or focal findings present) 1
- No sputum culture 1
- No viral PCR testing 1
- No C-reactive protein or procalcitonin 1
- No spirometry or peak flow at initial presentation 1
Treatment: What NOT to Prescribe
The 2020 CHEST guidelines explicitly recommend against routine prescription of: 1
- Antibiotic therapy 1
- Antiviral therapy 1
- Antitussives 1
- Inhaled beta-agonists 1
- Inhaled anticholinergics 1
- Inhaled corticosteroids 1
- Oral corticosteroids 1
- Oral NSAIDs 1
Why antibiotics don't work and cause harm:
- Respiratory viruses cause 89-95% of acute bronchitis cases 4, 3, 5
- Antibiotics reduce cough duration by only 0.5 days (approximately 12 hours) 1, 2
- Antibiotics significantly increase adverse events (RR 1.20; 95% CI 1.05-1.36) 1
- Purulent sputum occurs in 89-95% of viral cases and does NOT indicate bacterial infection 2, 3
Essential Patient Education
Inform patients about the expected natural course: 2, 3, 5
- Cough typically lasts 10-14 days after the visit 1, 2
- Symptoms may persist up to 3 weeks total 1, 2
- The condition is self-limiting and will resolve without antibiotics 1
Communication strategies to improve satisfaction: 6, 3
- Refer to the condition as a "chest cold" rather than "bronchitis" to reduce antibiotic expectations 2, 3
- Patient satisfaction depends more on physician-patient communication than whether antibiotics are prescribed 6, 7
- Explain that antibiotics expose patients to adverse effects while contributing to antibiotic resistance without providing benefit 2, 3
When to Reassess
Instruct patients to return if: 1, 8
- Fever persists beyond 3 days (suggests bacterial superinfection or pneumonia) 1, 9
- Cough persists beyond 3 weeks (consider other diagnoses: asthma, COPD, pertussis, GERD) 1, 8
- Symptoms worsen rather than gradually improve 1
At reassessment, consider targeted investigations: 1
Exception: Pertussis
If pertussis is confirmed or strongly suspected: 1, 2
- Prescribe a macrolide antibiotic (erythromycin or azithromycin) immediately 1, 2
- Isolate the patient for 5 days from start of treatment 1, 2
- Early treatment within the first few weeks diminishes coughing paroxysms and prevents disease spread 1, 2
Optional Symptomatic Measures (Low-Risk)
May consider in select patients: 2
- Elimination of environmental cough triggers 2
- Vaporized air treatments 2
- Beta-2 agonist bronchodilators ONLY in patients with accompanying wheezing 2
- Codeine or dextromethorphan for bothersome dry cough that disturbs sleep 2, 8
Critical Pitfalls to Avoid
- Do not assume bacterial infection based on sputum color or purulence—this occurs in 89-95% of viral cases 2, 3
- Do not prescribe antibiotics based on cough duration alone—viral bronchitis cough normally lasts 10-14 days 2, 3
- Do not overlook undiagnosed asthma—up to 65% of patients with recurrent "acute bronchitis" episodes actually have mild asthma 1, 2
- Do not forget to check for chronic lung disease—these guidelines apply only to immunocompetent adults without COPD, asthma, or bronchiectasis 1