What is the brand name for immediate‑release oxycodone (oxycodone hydrochloride)?

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Brand Names for Immediate-Release Oxycodone

Roxicodone is the primary brand name for immediate-release oxycodone hydrochloride. 1

Available Brand Names and Formulations

Single-Entity Immediate-Release Oxycodone

  • Roxicodone: The most commonly referenced brand name for IR oxycodone hydrochloride in clinical guidelines 1, 2
  • OxyNorm: Available as capsules and oral solution for immediate-release formulation 3
  • Oxecta: An abuse-deterrent formulation of IR oxycodone using Aversion Technology 2
  • RoxyBond: A novel abuse-deterrent immediate-release formulation 4

Combination Products with Acetaminophen

  • Percocet: Oxycodone combined with acetaminophen (maximum 325 mg acetaminophen per tablet) 1
  • Percolone: Another oxycodone/acetaminophen combination product 1

Combination Products with Other Agents

  • Percodan: Oxycodone combination product 1

Important Clinical Distinctions

Immediate-Release vs Extended-Release

  • IR formulations (Roxicodone, OxyNorm) have onset within 10-30 minutes and duration of 3-6 hours 5, 3
  • ER formulations (OxyContin) have onset around 1 hour and duration of 10-12 hours, and should NOT be used for acute pain 1, 5

Prescribing Considerations

  • The CDC recommends initiating opioid therapy with immediate-release formulations rather than extended-release products 5
  • When prescribing, specify both the release mechanism (IR vs ER) and dose to avoid confusion 5
  • IR oxycodone is a Schedule II controlled substance 1
  • Initial dosing for IR oxycodone is typically 5-15 mg every 4-6 hours as needed 1

References

1
Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

3
Research

Oxycodone: a pharmacological and clinical review.

Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2007

5
Guideline

Oxycodone Formulations and Prescribing Guidelines

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

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Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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