Symptoms of Bipolar Disorder
Bipolar disorder presents with distinct manic (or hypomanic) and depressive episodes, each with characteristic symptom clusters that represent a significant departure from baseline functioning.
Manic Episode Symptoms
A manic episode lasting ≥7 days (or requiring hospitalization) includes the following core features:
- Marked euphoria, grandiosity, and irritability that represent a clear change from the person's usual state 1
- Reduced need for sleep (a hallmark sign) without feeling tired 1
- Increased energy and hyperactivity with excessive involvement in risky activities 2
- Rapid, pressured speech and racing thoughts 2
- Mood lability with rapid and extreme mood shifts 1
- Psychotic features such as paranoia, confusion, grandiose delusions, or florid psychosis may be present 1, 2
- Psychomotor, sleep, and cognitive changes accompany the mood disturbance 1
- Impairment across multiple settings (not isolated to one environment), distinguishing true mania from situational reactions 1
Hypomanic Episode Symptoms
Hypomania is a milder elevation lasting ≥4 days with similar but less severe features:
- Elevated, expansive, or irritable mood plus at least three additional symptoms (four if mood is solely irritable) 1, 3
- No marked impairment or need for hospitalization (this is the key distinction from full mania) 1, 3
- Spontaneous mood change not merely reactive to situational stressors 1
- Sleep disturbances and psychomotor activation accompanying the mood shift 1
Depressive Episode Symptoms
Depressive episodes in bipolar disorder are characterized by:
- Psychomotor retardation with slowed thinking, difficulty concentrating, and indecisiveness 1, 3
- Hypersomnia (excessive sleep) rather than insomnia 1, 3
- Pervasive sadness, feelings of emptiness, and anhedonia (inability to experience pleasure) 1
- Suicidality with significant suicide attempts 1, 3
- Psychotic features are often present 1, 3
- Feelings of worthlessness and guilt 2
Mixed Episode Symptoms
Mixed episodes (≥7 days) involve simultaneous presence of both manic and depressive symptoms:
- Full criteria for both manic and depressive episodes met concurrently 1, 2
- Prominent depressive symptoms (worthlessness, guilt, anhedonia) occurring during a manic episode 2
- Concurrent symptoms, not sequential episodes separated by wellness 1
Episode Patterns and Cycling
The temporal pattern of episodes helps characterize bipolar disorder:
- Rapid cycling: Four or more mood episodes in one year 1
- Ultrarapid cycling: 5-364 cycles per year 1
- Ultradian cycling: More than 365 cycles per year 1
- Episodes represent a cyclical nature with distinct episode boundaries in adults 1
Age-Specific Presentation Differences
Children and adolescents present differently than adults:
- In children: Markedly labile and erratic mood, energy, and behavior changes; irritability and belligerence more common than euphoria; high rates of comorbid disruptive disorders 1
- In adolescents: Frequently associated with psychotic symptoms, markedly labile moods, mixed manic-depressive features; more chronic and refractory to treatment than adult-onset cases 1, 3
- In adults: Episodes represent clearer departure from baseline with more classic presentation and distinct episode boundaries 1
Warning Signs and Risk Factors
Certain features increase suspicion for bipolar disorder:
- Premorbid anxiety and dysphoria are common 1
- Approximately 20% of youths with major depression develop manic episodes by adulthood 1
- Risk factors in depressed patients: Rapid onset, psychomotor retardation, psychotic features, family history of affective disorders, history of mania/hypomania after antidepressant treatment 1
- Strong family history of bipolar disorder increases likelihood of true bipolar disorder 1
Critical Diagnostic Distinctions
When evaluating irritability and agitation, assess for:
- Euphoria or grandiosity first—their presence strongly suggests bipolar disorder rather than other conditions 1
- Marked changes in mental/emotional state rather than reactions to situations 1
- Impairment across different realms of life, not isolated to one setting 1
- Episode duration: Mood episodes lasting <4 days do not meet hypomania criteria and should be classified as Bipolar Disorder NOS 1