No Active Recall on Gabapentin
There is no current FDA recall on gabapentin. The question appears to be asking about drug safety alerts or product withdrawals, and the available evidence does not indicate any active recall of gabapentin products.
Context on Drug Recalls
The evidence provided includes general information about FDA drug recall characteristics but does not mention any specific gabapentin recall 1. The most common reasons for drug recalls historically include contamination, mislabeling, adverse reactions, defective products, and incorrect potency 1.
Important Safety Considerations for Gabapentin
While there is no recall, clinicians should be aware of several important safety issues:
Emerging Misuse Liability
- Gabapentin misuse has risen significantly, particularly when combined with opioids 2
- Misuse typically occurs for purposes of eliciting euphoric effects, enhancing other substances, or self-treating withdrawal, pain, anxiety, or insomnia 2
- Gabapentinoids significantly increase opioid-related morbidity and mortality when used concomitantly 2
- Several US states have begun reclassifying gabapentin as a controlled substance or mandating reporting to prescription drug monitoring programs 2
Respiratory Compromise Risk
- Assess oxygen saturation and respiratory rate in patients experiencing respiratory symptoms while on gabapentin 3
- Renal impairment can lead to gabapentin accumulation and increased side effects 3
Appropriate Clinical Use
- Gabapentin is NOT recommended for episodic migraine prevention (weak recommendation against) 4
- Gabapentin is effective for neuropathic pain conditions including diabetic neuropathy (NNT 2.9) and postherpetic neuralgia (NNT 3.9) 5
- For chemotherapy-induced peripheral neuropathy, gabapentin showed no benefit in placebo-controlled trials 4