For an elderly patient with ischemic heart disease who underwent coronary artery bypass grafting and subsequently died from septicemia causing multiorgan failure, which should be recorded as the primary cause of death on the death certificate?

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Primary Cause of Death: Septicemia

Septicemia should be recorded as the primary cause of death on this patient's death certificate. 1, 2

Rationale for Death Certificate Completion

The primary cause of death represents the final disease or condition that directly resulted in death, not the underlying chronic condition that predisposed the patient to complications. 1 In this case, the causal chain clearly progressed from surgical site infection → septicemia → multiorgan failure → death. 1

The American College of Cardiology/American Heart Association guidelines explicitly recommend that death should be attributed to the specific proximate cause rather than distant underlying conditions. 1, 2 This means septicemia is the correct primary cause despite the patient's cardiac history. 1

Proper Death Certificate Structure

The death certificate should be completed as follows:

Part I (Direct causal sequence):

  • Immediate cause: Multiorgan failure
  • Due to: Septicemia
  • Due to: Surgical site infection post-CABG 2

Part II (Contributing conditions):

  • Ischemic heart disease 2

The ACC/AHA guidelines provide clear classification for death attribution by physiological system, listing "Infection" as a distinct primary cause of death category separate from cardiovascular causes. 2 The underlying ischemic heart disease contributed to the patient's complications but was not the direct cause of death. 1

Why Other Options Are Incorrect

  • CABG (Option D): The surgery itself is not listed as a cause of death; rather, the complication arising from it (surgical site infection leading to septicemia) is the cause. 3

  • Ischemic heart disease (Option B): While this is the underlying condition that necessitated surgery, it did not directly cause death. 1 It should be listed in Part II as a contributing condition, not as the primary cause. 2

  • Congestive heart failure (Option C): There is no indication this patient died from heart failure; the clinical scenario describes death from septicemia-induced multiorgan failure. 4

Clinical Context Supporting This Determination

Septicemia following cardiac surgery carries exceptionally high mortality, with rates of 20-50% depending on severity. 2 Post-operative sepsis in cardiac surgery patients has a 16-fold higher mortality compared to those without sepsis. 1 When septicemia progresses to multiorgan failure, mortality rates reach 32-46%. 1

The most common cause of death in sepsis-related ARDS and multiorgan failure is unresolved sepsis or multisystem organ failure, not the underlying cardiac disease. 4 This reinforces that the infectious process supersedes the cardiac history in determining cause of death. 1

Key Principle

The World Health Organization defines cause of death as the disease or injury that initiates a chain of events leading to death. 3 In this case, that initiating event was the surgical site infection that progressed to septicemia, not the ischemic heart disease that led to the need for surgery. 3

References

Guideline

Primary Cause of Death: Septicemia

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2026

Guideline

Primary Cause of Death: Septicemia

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Death certification: a primer. Part II--The cause of death statement.

South Dakota medicine : the journal of the South Dakota State Medical Association, 2014

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

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Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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