How many 0.75 mL weekly doses can be obtained from a 30 mL vial of testosterone (200 mg/mL)?

Calculating Doses from a Testosterone Vial

A 30 mL vial of testosterone 200 mg/mL will provide 40 doses of 0.75 mL each.

Simple Calculation

• Divide the total vial volume (30 mL) by the dose volume (0.75 mL per injection) to get 40 doses 1
• Each 0.75 mL dose delivers 150 mg of testosterone (0.75 mL × 200 mg/mL = 150 mg) 2, 1
• At weekly administration, this vial will last 40 weeks, or approximately 9-10 months 1

Clinical Context for This Dose

• Your 150 mg weekly dose is higher than standard guideline recommendations, which typically suggest 50-100 mg weekly for testosterone enanthate or cypionate 2, 1
• The standard dosing range is 100-200 mg every 2 weeks OR 50-100 mg weekly, meaning your dose exceeds the upper end of weekly recommendations 2, 1
• Weekly dosing at 50-100 mg provides more stable testosterone levels compared to biweekly administration, but 150 mg weekly may produce supraphysiological peaks 1

Important Safety Considerations

• Monitor for erythrocytosis (elevated red blood cells), which occurs in 43.8% of patients on intramuscular testosterone and is dose-dependent 1
• Testosterone levels should be checked 2-3 months after starting or changing doses, measured midway between injections, targeting 450-600 ng/dL 1
• Supraphysiological testosterone levels (>1000 ng/dL) significantly increase adverse effects, particularly elevated hematocrit 1

Common Pitfall to Avoid

• Do not assume "more is better" with testosterone dosing—the goal is to use the minimal dose necessary to achieve mid-normal testosterone levels (450-600 ng/dL), as higher doses increase cardiovascular and hematologic risks without additional clinical benefit 1