Can Castleman disease cause macrocytosis?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: February 10, 2026View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Related Questions

What is the appropriate diagnosis and treatment for an adult patient presenting with necrotizing lymphadenitis, suspected to have multicentric Castleman disease?
What are the treatment options for Castleman disease?
What is the treatment approach for Castleman disease in patients with Systemic Lupus Erythematosus (SLE)?
What are the treatment options for Castleman disease?
What is the treatment approach for Castleman disease?
What are the differential diagnoses and recommended work‑up for a patient with low hemoglobin, markedly increased mean corpuscular volume, elevated red‑cell distribution width, and an inappropriately low absolute reticulocyte count?
What is the recommended intravenous antibiotic regimen for cellulitis of the lower extremities in a 59‑year‑old man with diabetes?
In this female patient, does the chest X‑ray demonstrate pleural fluid or pneumonia?
What ICD‑10‑CM code best supports insurance approval of extended‑release oxycodone for a patient with severe levoconvex lumbar scoliosis (apex at L1), multilevel lumbar spinal stenosis (L1‑L5), bilateral 10/10 radicular leg pain refractory to maximal pregabalin (600 mg BID), amitriptyline, and duloxetine, and who cannot use NSAIDs due to cardiac risk and acute kidney injury?
What is the differential diagnosis and appropriate work‑up for a patient with non‑immune hemolytic anemia (low haptoglobin, elevated reticulocyte count, negative direct antiglobulin (Coombs) test), macrocytosis, mild leukopenia, and a low absolute CD4⁺ T‑cell count?
What is the appropriate management for a 59-year-old man with a serum 25-hydroxyvitamin D level of 21 ng/mL?

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.