Differential Diagnosis for Swollen Lip with Pain and Tingling
Single Most Likely Diagnosis
- Herpes Simplex Virus (HSV) Infection: This is the most likely diagnosis given the symptoms of a swollen lip with pain and tingling. HSV infections are common and can cause these symptoms, especially if the patient has a history of cold sores or fever blisters.
Other Likely Diagnoses
- Angular Cheilitis: This condition causes inflammation of the corners of the mouth and can lead to swelling, pain, and tingling. It's often associated with fungal or bacterial infections.
- Trauma or Injury: A physical injury to the lip can cause swelling, pain, and tingling, especially if the injury is recent.
- Allergic Reaction: An allergic reaction to a food, cosmetic, or other substance can cause lip swelling, pain, and tingling.
- Dental Problems: Issues like a tooth abscess or gum infection can radiate pain to the lip and cause swelling and tingling.
Do Not Miss Diagnoses
- Lymphoma or Other Cancers: Although rare, cancers like lymphoma can cause swelling and pain in the lip. It's crucial to consider this possibility, especially if the swelling is persistent and unexplained.
- Neurological Conditions: Conditions like trigeminal neuralgia can cause severe pain and tingling in the face, including the lip.
- Infections like Cellulitis or Abscess: Bacterial infections can cause severe swelling, pain, and tingling, and require prompt antibiotic treatment.
Rare Diagnoses
- Sarcoidosis: This autoimmune disease can cause swelling and pain in various parts of the body, including the lips.
- Melkersson-Rosenthal Syndrome: A rare neurological disorder that can cause facial swelling, including lip swelling, along with other symptoms like facial paralysis and difficulty speaking.
- Cheilitis Granulomatosa: A rare condition that causes chronic swelling of the lips, often accompanied by pain and tingling.