What vial volumes (in mL) are commercially available for injectable triamcinolone (e.g., Kenalog‑40, Kenacol‑80)?

Triamcinolone Vial Volumes

Injectable triamcinolone acetonide is commercially available in 10 mL multi-dose vials containing 40 mg/mL (400 mg total per vial). 1

FDA-Approved Formulations

The FDA-labeled triamcinolone acetonide injectable suspension comes in the following vial size:

• 10 mL multi-dose vial at 40 mg/mL concentration (providing 400 mg total triamcinolone acetonide per vial) 1

Historical Context and Alternatives

While the standard commercial formulation is 40 mg/mL in 10 mL vials, research has documented that Kenalog-40 (Bristol-Myers-Squibb) was historically supplied as 0.1 mL single-dose vials containing 40 mg for certain applications. 2 However, this smaller vial size is not the current standard FDA-approved packaging described in the drug label. 1

Preservative-Free Formulations

For specialized applications (particularly intravitreal use), preservative-free formulations have been prepared in research settings at concentrations of 40 mg/mL or 160 mg/mL in single-use vials, though these are not standard commercial products. 3 These preparations were developed specifically to avoid benzyl alcohol toxicity in ocular tissues. 4, 3

Storage Requirements

• Store at 20° to 25°C (68° to 77°F) 1
• Protect from temperatures below 20°C (68°F) 1
• Store vial in carton to protect from light 1
• Store vial upright 1
• Discard unused portions of single-dose vials 1