How should I manage an acute epistaxis?

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Last updated: February 13, 2026View editorial policy

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Managing Acute Epistaxis

Lean forward and apply firm, continuous pressure to the soft lower third of your nose for a full 10-15 minutes without checking if bleeding has stopped—this single maneuver resolves the vast majority of nosebleeds. 1, 2

Immediate First-Line Actions

Body Positioning

  • Sit upright with your head tilted slightly forward to prevent blood from flowing into your airway or stomach 2, 3
  • Breathe through your mouth and spit out blood rather than swallowing it 1, 4

Direct Nasal Compression

  • Pinch the soft lower third of the nose (not the bony bridge) with firm, sustained pressure for 10-15 minutes continuously 1, 2
  • Do not release pressure intermittently to check if bleeding has stopped—this is the most common cause of treatment failure 2
  • Compression alone stops bleeding in the vast majority of anterior nosebleeds 1, 2

If Bleeding Continues After 15 Minutes

Add Topical Vasoconstrictors

  • First, blow your nose gently or have clots removed to clear the nasal cavity 1
  • Spray oxymetazoline or phenylephrine (2 sprays) into the bleeding nostril 1, 2
  • This approach stops bleeding in 65-75% of emergency department cases that don't respond to compression alone 2, 5
  • Resume firm compression for another 5-10 minutes after applying the spray 1, 2
  • You may repeat this sequence once if needed 1

Important Caution

  • Vasoconstrictors carry increased risk of cardiac or systemic complications in patients with undiagnosed hypertension (present in approximately one-third of epistaxis patients) 2
  • Avoid repeated or prolonged use, as this can cause rebound congestion (rhinitis medicamentosa) 2

After Bleeding Stops: Prevention

Nasal Moisturization

  • Apply petroleum jelly or nasal saline gel to the inside of your nose 2-3 times daily 1, 2, 3
  • Use saline nasal sprays frequently throughout the day to keep nasal mucosa moist 1, 2
  • Run a humidifier at your bedside, especially in dry environments 1, 2

Activity Restrictions

  • Avoid nose blowing, strenuous activity, and heavy lifting for at least 7-10 days 1
  • Do not pick your nose or insert tissues/cotton into the nostrils 1

When to Seek Emergency Care

Go to the emergency department or call 911 if: 1, 3

  • Bleeding persists after 15-30 minutes of proper continuous compression with vasoconstrictors
  • Total bleeding duration exceeds 30 minutes over a 24-hour period
  • You feel weak, lightheaded, or dizzy from blood loss
  • You have signs of hemodynamic instability (rapid heart rate, low blood pressure)
  • Blood is flowing briskly down your throat despite forward positioning

Special Considerations

If You Take Blood Thinners

  • Do not stop your anticoagulant or antiplatelet medication (including aspirin) without medical evaluation 1, 2
  • These medications are prescribed to prevent serious cardiovascular events—the survival benefits typically outweigh bleeding risks 2
  • First-line local measures (compression, vasoconstrictors) should be attempted before considering medication adjustments 2, 4
  • If bleeding is severe, hold your next dose but seek immediate medical evaluation 1

If You Take NSAIDs

  • Continue your NSAID unless bleeding cannot be controlled with local measures 2
  • Standard epistaxis alone is not an indication to discontinue NSAIDs 2

Advanced Treatments (Performed by Medical Professionals)

If home measures fail, your healthcare provider may perform: 1, 2, 5

  • Nasal endoscopy to locate the bleeding source (successful in 87-93% of cases)
  • Cauterization of the bleeding vessel (electrocautery has 14.5% recurrence vs. 35.1% for chemical cautery)
  • Nasal packing with absorbable materials (required when compression, vasoconstrictors, and cautery fail)
  • Surgical arterial ligation (97% success rate) or endovascular embolization (80% success rate) for refractory cases

Common Pitfalls to Avoid

  • Releasing pressure prematurely before 10-15 minutes have elapsed 2
  • Tilting your head backward, which allows blood to flow into your throat 2, 3
  • Neglecting nasal moisturization after bleeding stops, leading to recurrent episodes 3, 4
  • Stopping prescribed anticoagulants without medical consultation 1, 2

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Epistaxis Management

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2026

Guideline

Management of Nasal Epistaxis

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Management of Epistaxis in Patients on Ozempic (Semaglutide)

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Epistaxis Treatment Options: Literature Review.

Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India, 2023

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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