Rationale for Comprehensive Pain Assessment
Assessing all dimensions of pain is essential because pain is fundamentally a multidimensional experience comprising sensory, affective, and evaluative components—each requiring distinct therapeutic approaches that cannot be determined from intensity measurement alone. 1
Pain as a Multidimensional Construct
Pain assessment must extend beyond simple intensity ratings because:
Sensory Dimension
- Quality (what pain feels like): Descriptors such as aching, throbbing, or pressure suggest somatic pain in skin, muscle, and bone; cramping or gnawing indicates visceral pain; shooting, sharp, or stabbing sensations point to neuropathic pain from nerve damage 1
- Location and radiation patterns: Spatial distribution helps identify pain syndromes and underlying pathophysiology 1
- Temporal patterns: Duration, onset, relief patterns, and whether pain occurs at rest versus with movement guide treatment selection 1
- Intensity: While important, this represents only one component of the pain experience 1
Affective Dimension
- Emotional impact: The extent to which pain is perceived as unpleasant, distressing, or unbearable directly influences treatment response 1
- Psychological distress: Depression and anxiety amplify pain perception and are more important determinants of disability than pain intensity or duration in many conditions 1
- Pain catastrophizing: Negatively distorted perceptions of pain as "awful, horrible, and unbearable" are strongly associated with increased brain activity in areas related to pain anticipation and emotional processing 2
Evaluative Dimension
- Functional interference: How pain impacts daily activities, work, social life, sleep patterns, appetite, sexual functioning, and mood determines treatment priorities 1
- Quality of life impact: The degree to which pain interferes with physical, psychological, role, and social functioning must guide therapeutic goals 1
Clinical Implications for Treatment Selection
Most patients with advanced cancer have at least two types of pain from different pathophysiologies, making comprehensive assessment mandatory for appropriate treatment selection. 1
Treatment Cannot Be Determined from Intensity Alone
- Nociceptive pain (somatic or visceral) responds to different interventions than neuropathic pain 1
- Providing only opioids to a patient with impending spinal cord compression is inappropriate—glucocorticoids and radiation therapy are required 1
- Pain quality descriptors directly improve therapy choice by identifying underlying mechanisms 1
Psychosocial Factors Predict Treatment Response
- Self-efficacy beliefs and fear avoidance are more important determinants of disability and functioning than pain intensity in many disorders 3
- Active coping strategies (functioning despite pain, distraction) associate with adaptive functioning, while passive strategies (withdrawal, relinquishing control) relate to greater pain and depression 2
- Psychological distress amplifies pain-related distress, and inadequately controlled pain causes substantial psychological distress—creating a bidirectional relationship that must be addressed. 1
Assessment Must Be Repeated Regularly
- Pain should be assessed at the first visit and at each subsequent visit occurring at least 7 days apart 1
- Regular reassessment using validated tools is the first step toward effective and individualized treatment 1
- Ongoing assessment clarifies the need for additional comprehensive evaluation and rational care planning 1
Common Pitfalls to Avoid
Focusing solely on pain intensity while ignoring quality, temporal patterns, and functional impact will result in inappropriate treatment selection and poor outcomes. 1
- Failing to assess pain descriptors prevents identification of neuropathic versus nociceptive mechanisms requiring different pharmacologic approaches 1
- Ignoring psychological factors (depression, anxiety, catastrophizing) leaves major treatment targets unaddressed, as these factors are often more important than pain intensity for predicting disability 1, 2
- Not evaluating functional interference misses the evaluative dimension that should guide treatment goals and intensity 1
- Assuming pain always results from organic pathology alone leads to inadequate assessment—psychosocial and behavioral factors must be integrated 4, 5