What is the significance of bilateral pleural effusion in Rheumatic Heart Disease (RHD)?

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Last updated: April 23, 2025View editorial policy

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Differential Diagnosis for Bilateral Pleural Effusion in Rheumatic Heart Disease (RHD)

  • Single most likely diagnosis
    • Congestive heart failure: This is the most likely diagnosis given the context of RHD, as congestive heart failure is a common complication of RHD and can lead to bilateral pleural effusions due to fluid overload.
  • Other Likely diagnoses
    • Pulmonary embolism: Although less common, pulmonary embolism can occur in patients with RHD, especially if they have atrial fibrillation, and can cause bilateral pleural effusions.
    • Pericardial effusion: RHD can also lead to pericardial effusion, which can cause bilateral pleural effusions due to the close proximity of the pericardial and pleural spaces.
  • Do Not Miss diagnoses
    • Malignancy (e.g., metastatic cancer): Although less likely, malignancy can cause bilateral pleural effusions and is a diagnosis that should not be missed due to its significant implications for treatment and prognosis.
    • Tuberculosis: In regions where tuberculosis is common, it should be considered as a potential cause of bilateral pleural effusions, especially if the patient has risk factors or symptoms suggestive of tuberculosis.
  • Rare diagnoses
    • Chylothorax: A rare condition characterized by the accumulation of chyle in the pleural space, which can occur in patients with RHD due to obstruction of the thoracic duct.
    • Amyloidosis: A rare condition characterized by the deposition of amyloid proteins in various tissues, including the lungs, which can cause bilateral pleural effusions in patients with RHD.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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