Clinical Evaluation of Foot Drop
Begin by performing a focused neurological examination to localize the lesion along the motor pathway, testing ankle dorsiflexion strength (graded 0-5), examining sensory distribution patterns, and assessing deep tendon reflexes to differentiate between central (L5 radiculopathy) and peripheral (peroneal nerve) etiologies. 1, 2
Essential History Components
Onset and mechanism of injury: Determine if the foot drop was acute (suggesting traumatic nerve injury or disc herniation) or gradual (suggesting degenerative spinal disease or chronic nerve compression) 1, 2
Pain characteristics and distribution: L5 radiculopathy typically presents with radiating leg pain, while isolated peroneal nerve injury may have localized pain at the fibular head or be painless 1, 3
Associated symptoms: Ask about back pain, leg weakness, numbness distribution, and bowel/bladder dysfunction (red flags for cauda equina syndrome) 1, 3
Functional impact: Document difficulty with walking, frequency of tripping or falls, and ability to perform daily activities 1, 4
Duration of symptoms: Critical for determining surgical candidacy, as nerve reconstruction options diminish after 12 months 2, 4
Physical Examination Algorithm
Motor Testing
Grade ankle dorsiflexion strength using the Medical Research Council scale (0-5), as preoperative dorsiflexion power is the key prognostic factor 3, 2
Test toe extension (extensor hallucis longus and extensor digitorum longus) to assess deep peroneal nerve function 1, 2
Assess ankle eversion (peroneus longus and brevis) to evaluate superficial peroneal nerve function 1, 2
Examine hip abduction strength (gluteus medius, L5 innervation) to help differentiate radiculopathy from peripheral nerve lesions 1, 3
Sensory Examination
Map sensory deficits in the L5 dermatome (dorsum of foot, first web space) versus superficial peroneal distribution (dorsolateral foot) 1, 2
Test pinprick and light touch in these distributions to localize the lesion 1
Reflex Testing
Check ankle reflexes (S1), which should be normal in L5 radiculopathy and peroneal nerve lesions 1
Assess patellar reflexes (L4), which help exclude higher lumbar pathology 1
Specialized Maneuvers
Tinel's sign at the fibular head: Tap over the peroneal nerve as it wraps around the fibular neck; a positive test (tingling in the distribution) suggests peroneal nerve compression 1, 2
Straight leg raise test: Positive test (radicular pain with leg elevation <70 degrees) suggests L5 radiculopathy from disc herniation 3
Observe gait pattern: Note compensatory hip hiking or circumduction during swing phase, which indicates functional impairment 1, 4
Diagnostic Localization Strategy
The most common causes are L5 radiculopathy (typically at L4/5 level) and peroneal nerve injury at the fibular head. 1, 3
Findings Suggesting L5 Radiculopathy:
- Back pain with radiation down the leg 3
- Weakness in hip abduction (gluteus medius) in addition to ankle dorsiflexion 1, 3
- Sensory loss in the entire L5 dermatome (lateral leg and dorsum of foot) 1
- Positive straight leg raise test 3
Findings Suggesting Peroneal Nerve Lesion:
- Localized tenderness or Tinel's sign at the fibular head 1, 2
- Isolated weakness in ankle dorsiflexion and eversion without hip weakness 1, 2
- Sensory loss limited to the superficial peroneal distribution (dorsolateral foot) 1
- History of trauma, prolonged leg crossing, or recent weight loss 1, 2
Additional Testing Considerations
Electrodiagnostic studies (EMG/NCS) should be ordered to confirm the diagnosis, localize the lesion, assess severity of nerve injury, and establish baseline for monitoring recovery 1, 2
MRI of the lumbar spine is indicated when L5 radiculopathy is suspected based on clinical findings 1, 3
MRI of the knee/leg may be warranted if a mass lesion or structural abnormality is suspected at the fibular head 1, 2
Critical Pitfalls to Avoid
Do not assume a single etiology: Foot drop can result from lesions at multiple locations along the motor pathway simultaneously 1
Do not delay evaluation: Early diagnosis is essential, as surgical options for nerve reconstruction become limited after 12 months from injury 2, 4
Do not overlook central causes: Always assess for upper motor neuron signs (spasticity, hyperreflexia, Babinski sign) that would indicate brain or spinal cord pathology 1
Do not miss compressive neuropathy: Any patient with clinically suspected peroneal nerve compression at the fibular head should be informed about surgical decompression options, which can be performed with minimal risk 1