What are the recommended doses of induction agents and neuromuscular blocking agents for rapid sequence intubation in a 70‑kg adult and in children ≤12 years, and how should they be adjusted for severe hypotension, increased intracranial pressure, obesity, and renal or hepatic impairment?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: February 17, 2026 • View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Related Questions

Should Rapid Sequence Intubation (RSI) medications be used during Cardiopulmonary Resuscitation (CPR) intubation in adult patients with cardiac arrest or severe respiratory distress?
What is the mechanism of action (MOA) of Rapid Sequence Intubation (RSI) drugs?
Do you induce paralysis first in Rapid Sequence Intubation (RSI)?
What medications are used before intubation in emergency and elective settings, considering patient's medical history and health status?
What are the recommended drugs for intubation in a typical adult patient in the Emergency Room (ER) setting?
In a patient with vitamin B12 (cobalamin) deficiency and a low serum folate (<6 ng/mL), should folic acid be administered before correcting the B12 deficiency, and what is the recommended treatment regimen?
In a 9-year-old child with alpha‑thalassemia who presents with a cough suggestive of bacterial infection, which antibiotic should be prescribed?
What is the recommended initial emergency treatment for diabetic ketoacidosis in an adult patient without contraindications?
What are the recommended weight‑based intravenous doses and corresponding volumes (mL) of fentanyl, midazolam, and succinylcholine for rapid sequence intubation in an adult patient (≥18 years)?
When are systemic corticosteroids indicated in aspiration pneumonia and what dosing regimen and monitoring are recommended?
What is the appropriate work‑up and management for a patient presenting with trace ketonuria and bilateral lower‑extremity edema?

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.

Ask Question