What are Fordyce spots (sebaceous gland hyperplasia)?

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Last updated: April 23, 2025View editorial policy

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From the Research

Fordyce spots are harmless and do not require treatment, as they are a normal anatomical variant, not a disease or infection. They are simply enlarged sebaceous glands that are visible through the skin. If you're concerned about their appearance, a dermatologist can confirm the diagnosis and discuss cosmetic options like laser therapy or chemical peels, though these are rarely recommended due to potential scarring.

Key Points to Consider

  • Fordyce spots affect up to 80% of adults, tend to become more noticeable with age, and don't indicate any underlying health issues 1.
  • They cannot be transmitted to others and don't cause any symptoms beyond their appearance.
  • Maintaining good hygiene is recommended, but no special care is required.
  • If you notice any changes in the spots, such as bleeding, pain, or rapid growth, consult a healthcare provider to rule out other conditions.

Treatment Options

  • Laser therapy, such as CO2 laser, has been shown to be effective in treating Fordyce spots, with excellent cosmetic results and no side effects 2.
  • Other treatment options, such as isotretinoin, have also been reported to be effective in some cases, although the response can be dichotomous and long-term results are not well documented 1.
  • Intralesional electrocoagulation using a proximally insulated microneedle and monopolar radiofrequency device has also been reported to be effective in treating Fordyce spots, with marked cosmetic improvements without surface damage 3.

Recommendations

  • No treatment is necessary for Fordyce spots, as they are a normal anatomical variant, not a disease or infection.
  • If you're concerned about their appearance, consult a dermatologist to discuss cosmetic options and determine the best course of treatment.
  • It's essential to prioritize morbidity, mortality, and quality of life when considering treatment options for Fordyce spots, and to weigh the potential benefits and risks of each treatment option.

References

Research

Treatment of Fordyce spots with CO2 laser.

Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 2003

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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