What is the diagnosis for a 26-year-old female presenting with nausea, emesis, intermittent fevers, upper abdominal pain, watery loose stools 2-3 times a day, and fatigue, despite difficulty eating and keeping food down for over one week?

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Differential Diagnosis for 26 yo Female with Gastrointestinal Symptoms

  • Single most likely diagnosis:
    • Viral Gastroenteritis: This is the most likely diagnosis given the symptoms of nausea, emesis, fevers, upper abdominal pain, and watery loose stools. The duration of over 1 week and the difficulty eating and keeping food down are consistent with a viral etiology.
  • Other Likely diagnoses:
    • Food Poisoning: The symptoms of nausea, vomiting, abdominal pain, and diarrhea could be consistent with food poisoning, especially if the patient has a history of consuming undercooked or contaminated food.
    • Inflammatory Bowel Disease (IBD): Although less likely, IBD (e.g., Crohn's disease or ulcerative colitis) could present with similar symptoms, including abdominal pain, diarrhea, and weight loss.
    • Giardiasis: This parasitic infection can cause prolonged gastrointestinal symptoms, including diarrhea, abdominal pain, and weight loss, especially in individuals who have traveled or been exposed to contaminated water.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.):
    • Appendicitis: Although the symptoms are not typical, appendicitis can present with nausea, vomiting, and abdominal pain, and it is a surgical emergency.
    • Intestinal Obstruction: This condition can cause severe abdominal pain, nausea, vomiting, and obstipation, and requires prompt surgical intervention.
    • Ectopic Pregnancy: In a female patient of childbearing age, ectopic pregnancy must be considered, especially if there is a history of missed periods or abdominal pain.
  • Rare diagnoses:
    • Whipple's Disease: A rare bacterial infection that can cause malabsorption, weight loss, and gastrointestinal symptoms.
    • Celiac Disease: An autoimmune disorder that can cause malabsorption, diarrhea, and abdominal pain in response to gluten ingestion.
    • Tropical Sprue: A rare condition that can cause malabsorption, diarrhea, and weight loss, often associated with travel to tropical regions.

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This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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