What are the treatment options for Attention Deficit Disorder (ADD)?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: April 23, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

From the Guidelines

Treatment options for Attention Deficit Disorder (ADD) include both medication and non-medication approaches, with stimulants such as methylphenidate and amphetamine-based medications being first-line treatments, and non-stimulant medications like atomoxetine and guanfacine as alternatives, alongside behavioral therapy and lifestyle modifications. The medication options for ADD include:

  • Stimulants:
    • Methylphenidate (Ritalin, Concerta) at doses ranging from 5-60mg daily
    • Amphetamine-based medications (Adderall, Vyvanse) at 5-70mg daily, adjusted based on response and side effects 1
  • Non-stimulants:
    • Atomoxetine (Strattera) at 40-100mg daily
    • Guanfacine (Intuniv) at 1-4mg daily
    • Clonidine, with a transdermal patch available, and twice daily dosing necessary 1 These medications work by increasing neurotransmitters like dopamine and norepinephrine in the brain, improving attention and executive function. Non-medication approaches are equally important and include:
  • Behavioral therapy:
    • Cognitive-behavioral therapy
    • Organizational skills training
    • Parent training
  • Lifestyle modifications:
    • Educational accommodations
    • Regular exercise
    • Adequate sleep (7-9 hours nightly)
    • Consistent routines
    • Mindfulness practices
    • Reducing distractions in work environments Treatment is typically long-term, with medication adjustments as needed, and works best when combining medication with behavioral strategies tailored to individual needs and symptoms 1.

From the FDA Drug Label

Atomoxetine capsules are indicated as an integral part of a total treatment program for ADHD that may include other measures (psychological, educational, social) for patients with this syndrome. Appropriate educational placement is essential in children and adolescents with this diagnosis and psychosocial intervention is often helpful When remedial measures alone are insufficient, the decision to prescribe drug treatment medication will depend upon the physician’s assessment of the chronicity and severity of the patient’s symptoms.

The treatment options for ADHD include:

  • Pharmacological treatment: Atomoxetine capsules
  • Psychological measures
  • Educational measures
  • Social measures
  • Psychosocial intervention
  • Appropriate educational placement 2

From the Research

Treatment Options for Attention Deficit Hyperactivity Disorder (ADHD)

The following treatment options are available for ADHD:

  • Pharmacological interventions:
    • Stimulants: methylphenidate (MPH) 3, 4, 5, 6, dextroamphetamine (DEX) 3, amfetamine 6
    • Non-stimulants: atomoxetine 4, alpha-2 adrenergic receptor agonists 4, antipsychotics 4, tricyclic antidepressants 3, 4, bupropion 4, modafinil 4, venlafaxine 4, 5
  • Non-pharmacological interventions:
    • Behavioral therapies 3, 7
    • Physical activity 7
  • Combination therapies: combining stimulants or non-stimulants with behavioral therapies or physical activity 3, 4, 7

Efficacy of Treatment Options

The efficacy of these treatment options varies:

  • Stimulants: effective in reducing ADHD symptoms in children and adults 3, 4, 5, 6
  • Non-stimulants: effective in reducing ADHD symptoms in children and adults, but with varying degrees of efficacy 4
  • Behavioral therapies: effective in reducing ADHD symptoms, but with limited evidence 3, 7
  • Physical activity: effective in reducing ADHD symptoms and improving social impairment in children 7

Safety and Adverse Effects

The safety and adverse effects of these treatment options also vary:

  • Stimulants: associated with mild and short-term side effects, such as insomnia and appetite suppression 3, 5
  • Non-stimulants: associated with varying degrees of adverse effects, such as nausea and headache 4
  • Behavioral therapies: generally considered safe, but with limited evidence 3, 7
  • Physical activity: generally considered safe, but with limited evidence 7

Related Questions

What is the maximum dose of Adzenys (amphetamine)?
What is Mydayis (amphetamine)?
Is there evidence to support combining short-acting and long-acting stimulant medications, such as methylphenidate (Ritalin) and Concerta (methylphenidate extended-release), for a patient with Attention Deficit Hyperactivity Disorder (ADHD)?
Can a 26-year-old patient taking Concerta (methylphenidate) for Attention Deficit Hyperactivity Disorder (ADHD) as needed (PRN) safely take phentermine for weight loss, given a refusal to use Glucagon-Like Peptide-1 (GLP-1) receptor agonists due to needle phobia?
What is the best approach to manage a patient with a history of Attention Deficit Hyperactivity Disorder (ADHD), Generalized Anxiety Disorder (GAD), and autism spectrum disorder, who is currently on Intuniv (guanfacine), Strattera (atomoxetine), and Trazodone?
What are the treatment options for Multiple Sclerosis (MS) related chronic fatigue?
What is the most common complication post Endoscopic Retrograde Cholangiopancreatography (ERCP), acute pancreatitis or duodenal perforation?
What is the most common complication post Endoscopic Retrograde Cholangiopancreatography (ERCP), acute pancreatitis or duodenal perforation?
Is diphenhydramine (Benadryl) safe to use after a cerebrovascular accident (CVA) or stroke?
Is this a case of anemia of chronic disease with low iron (Iron) levels, elevated ferritin (Ferritin) levels, low iron saturation (Iron Saturation), elevated total iron-binding capacity (TIBC), and low hemoglobin (Hg), and will iron therapy be necessary?
Can meclizine (antihistamine) help with pruritus (itching)?

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.