From the Research
Pyridium (phenazopyridine) is available over-the-counter in the United States, typically in lower doses (95-97.5mg) compared to prescription strength (100-200mg). You can find over-the-counter phenazopyridine under brand names like AZO Standard, UTI Relief, and various store brands in most pharmacies. These products are specifically marketed for urinary pain relief and are typically used for temporary relief of urinary symptoms like pain, burning, urgency, and frequency, often associated with urinary tract infections. The medication works by directly numbing the urinary tract lining rather than treating the infection itself, as shown in a study published in 2021 1. It's essential to note that phenazopyridine should only be used for 2-3 days, and you should see a healthcare provider if symptoms persist, as the underlying cause needs treatment. Some key points to consider when using phenazopyridine include:
- The medication causes orange-red discoloration of urine and can stain clothing.
- It should be avoided by those with kidney disease or G6PD deficiency.
- A study from 2020 2 demonstrated the efficacy and safety of phenazopyridine for symptomatic therapy in patients with acute uncomplicated cystitis.
- Another study from 2021 1 showed that the combination of fosfomycin and phenazopyridine was more effective than the combination of fosfomycin and drotaverine for the treatment of acute uncomplicated cystitis.
- However, it is crucial to be aware that some consumers may use over-the-counter phenazopyridine inappropriately, as highlighted in a study from 2003 3, which found that 51% of respondents used the medication inappropriately, and 38% substituted it for medical care.
- Additionally, a study from 2004 4 found that many consumers possess poor knowledge about phenazopyridine, potentially leading to undertreatment, especially in groups with worse access to care.
- Therefore, it is vital to use phenazopyridine judiciously and under the guidance of a healthcare provider when necessary.