My 11‑month‑old infant with fever and prior non‑bilious vomiting is now vomiting yellow (bilious) material—what immediate steps should be taken?

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Bilious Vomiting in an 11‑Month‑Old with Fever: Immediate Action Required

An 11‑month‑old infant with fever who transitions from non‑bilious to bilious (yellow/green) vomiting requires immediate surgical evaluation, because bilious vomiting at any age is a surgical emergency until proven otherwise—midgut volvulus can cause intestinal necrosis within hours. 1, 2


Immediate Red‑Flag Recognition

  • Bilious vomiting indicates obstruction distal to the ampulla of Vater and mandates urgent assessment by a pediatric surgical team. 1, 2, 3
  • Midgut volvulus accounts for 20% of bilious vomiting cases in the first 72 hours of life but can present at any age, including 11 months, and requires immediate surgical consultation to prevent bowel necrosis. 1, 2
  • The combination of fever and bilious vomiting raises concern for both surgical pathology (malrotation with volvulus, intussusception) and infectious causes (sepsis, meningitis, urinary tract infection). 1, 2, 4

Immediate Stabilization Steps

1. Place the infant nil per os (NPO) immediately

  • Stop all oral intake to prevent further gastric distension and aspiration risk. 5, 3

2. Insert a nasogastric or orogastric tube for gastric decompression

  • Decompress the stomach to relieve distension and reduce the risk of aspiration. 2, 3

3. Assess hydration status and initiate IV access

  • Evaluate for signs of severe dehydration (≥10% fluid deficit): prolonged skin tenting >2 seconds, cool extremities, decreased capillary refill, lethargy. 2
  • Establish intravenous access and begin fluid resuscitation with isotonic crystalloid (normal saline or lactated Ringer's) if dehydration is present. 2

4. Obtain immediate surgical consultation

  • Contact pediatric surgery before completing the imaging workup, because bilious vomiting is a surgical emergency. 1, 2, 3

Diagnostic Imaging Pathway

First‑Line Imaging: Plain Abdominal Radiographs

  • Obtain supine and cross‑table lateral (or left lateral decubitus) abdominal X‑rays as the initial imaging study. 1, 2, 5
  • Look for:
    • "Double bubble" sign (duodenal obstruction, most commonly duodenal atresia or malrotation with volvulus). 1, 2
    • "Triple bubble" sign with absent distal gas (jejunal atresia). 1, 2
    • Dilated bowel loops, air‑fluid levels, or pneumatosis intestinalis (suggesting obstruction or necrotizing enterocolitis). 5, 3

Second‑Line Imaging: Upper GI Series

  • If plain films show non‑classic findings or only a few distended loops, proceed immediately to an upper GI series with water‑soluble contrast to rule out malrotation with volvulus. 1, 2
  • Plain radiographs miss up to 7% of malrotation cases, so a normal X‑ray does not exclude malrotation. 2
  • The upper GI series will demonstrate abnormal positioning of the duodenojejunal junction and a "corkscrew" appearance of the proximal small bowel if volvulus is present. 1

Ultrasound Consideration

  • If clinical features suggest intussusception (intermittent crampy pain, "currant‑jelly" stools, palpable abdominal mass), ultrasound is the initial imaging modality of choice. 2
  • However, intussusception typically presents with intermittent non‑bilious vomiting initially, and the transition to bilious vomiting suggests progression or an alternative diagnosis. 2, 6

Laboratory Evaluation

  • Obtain a complete blood count, electrolytes, blood gas, and blood culture to assess for sepsis, metabolic derangements, and dehydration severity. 1, 4
  • Check for metabolic alkalosis (hypochloremic, hypokalemic), which would suggest pyloric stenosis, though this is less likely at 11 months and with bilious vomiting. 5
  • Urinalysis and urine culture are indicated in febrile infants ≤3 months but remain important in an 11‑month‑old with fever and vomiting to exclude urinary tract infection. 1

Management Priorities

Fluid Resuscitation

  • Administer 20 mL/kg boluses of isotonic crystalloid (normal saline or lactated Ringer's) for signs of moderate to severe dehydration or shock. 2
  • Reassess perfusion, capillary refill, and mental status after each bolus. 2

Antibiotic Consideration

  • If the infant appears toxic (lethargy, poor perfusion, altered mental status), initiate empiric broad‑spectrum antibiotics (e.g., ceftriaxone 50 mg/kg IV) after obtaining blood and urine cultures, to cover for sepsis, meningitis, or urinary tract infection. 1, 4
  • Do not delay surgical consultation or imaging to administer antibiotics unless the infant is in septic shock. 1

Antiemetic Use

  • Antiemetics are contraindicated in this scenario because they may mask clinical deterioration and delay recognition of surgical pathology. 5, 4
  • Ondansetron is reserved for persistent vomiting in non‑surgical conditions (e.g., viral gastroenteritis) and should not be used when bilious vomiting is present. 4

Critical Pitfalls to Avoid

  • Never dismiss bilious vomiting as "just gastroenteritis." Even if fever and prior non‑bilious vomiting suggest a viral illness, the transition to bilious emesis changes the differential diagnosis entirely. 2, 7
  • Do not wait for imaging results to contact surgery. Midgut volvulus can cause irreversible bowel ischemia within hours, and surgical exploration may be required even if imaging is equivocal. 1, 2, 3
  • Do not rely on the absence of abdominal distension to rule out obstruction. Early or high obstructions (e.g., malrotation with volvulus) may present with bilious vomiting before significant distension develops. 1, 3
  • Avoid antidiarrheal or antimotility agents. These are ineffective, shift focus away from appropriate fluid therapy, and can cause serious complications including ileus and abdominal distention. 2

Disposition

  • Admit to the hospital for surgical evaluation, IV hydration, and close monitoring. 4, 3
  • If malrotation with volvulus is confirmed or strongly suspected, the infant requires emergent laparotomy to prevent bowel necrosis. 1, 2, 3
  • If imaging excludes surgical pathology and the infant remains febrile, continue evaluation for infectious causes (sepsis, meningitis, urinary tract infection, pneumonia) and manage accordingly. 1, 4

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Guideline Summary for Evaluation and Management of Vomiting in Children

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2026

Research

Management of a child with vomiting.

Indian journal of pediatrics, 2013

Guideline

Diagnostic and Management Guidelines for Non‑Bilious Vomiting in Preterm Infants

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2026

Research

Abdominal surgical emergencies in infants and young children.

Emergency medicine clinics of North America, 2003

Research

Clinical update: vomiting in infants.

Community practitioner : the journal of the Community Practitioners' & Health Visitors' Association, 2013

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Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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