Normal Adult Urine Output
Normal adult urine output ranges from 800-2000 mL per 24 hours, with a practical clinical target of approximately 1 liter per day for healthy individuals with normal renal function. 1, 2
Standard Reference Values
- The accepted normal range is 800-2000 mL per 24 hours in healthy adults 1
- A minimum acceptable output is at least 0.5 mL/kg/hour, which translates to approximately 840 mL/day for a 70 kg person 1
- The upper range of normal can extend to 3000 mL/day depending on fluid intake 1
Weight-Based Calculations
- The minimum normal threshold is 0.5 mL/kg/hour sustained over 24 hours, equaling 35 mL/hour or 840 mL/day minimum for a 70 kg adult 1
- For obese patients, adjusted body weight should be considered rather than actual body weight for these calculations 1
Pathological Thresholds
Oliguria (Low Output)
- Oliguria is defined as <0.5 mL/kg/hour for at least 6 hours, which equals <840 mL/day for a 70 kg person 1, 2
- The traditional clinical threshold for oliguria is <400 mL/day 1, 2, 3
- Severe oliguria requiring immediate intervention is <4 mL/kg over 8 hours, approximately <280 mL/8 hours for a 70 kg person 1
Anuria (Minimal Output)
Polyuria (Excessive Output)
- Polyuria is defined as >3 liters per 24 hours 1, 2
- Nocturnal polyuria specifically refers to >33% of 24-hour output occurring at night 1, 3
Important Clinical Caveats
- Urine output measurements become unreliable in patients receiving diuretics, as output is artificially increased without reflecting true kidney function 1
- Measurements are also unreliable in cirrhotic patients with ascites, who may be oliguric due to sodium retention despite normal kidney function 1
- 24-hour urine collection is more informative than spot measurements, and completeness can be verified by measuring urinary creatinine (men should excrete >15 mg/kg/day, women >10 mg/kg/day) 1
- A full 24-hour measurement is required to diagnose polyuria; single 12-hour collections should not be used 2
Context-Specific Targets
For patients at risk of calcium oxalate kidney stone formation, the target output is at least 2.5 liters per 24 hours, requiring fluid intake of 3.5-4 liters daily 1