Differential Diagnosis for Recurrent Right Cheek Swelling
Single Most Likely Diagnosis
- Angioedema: This condition is characterized by the rapid swelling of the skin and mucous membranes, often without an identifiable cause or allergy. It can be recurrent and may affect any part of the body, including the cheeks. The fact that the swelling is recurrent and seems to occur randomly makes angioedema a plausible explanation.
Other Likely Diagnoses
- Dental Abscess or Infection: An infection in the teeth or gums can cause swelling in the cheek area. Given the localization to one side, a dental issue could be a likely cause, especially if the patient has poor dental hygiene or a history of dental problems.
- Allergic Reaction: Despite the patient reporting no known allergies, it's possible that an unknown allergen could be causing the swelling. Allergic reactions can be unpredictable and may not always follow a clear pattern.
- Insect Bite or Sting: Reactions to insect bites or stings can cause localized swelling and may occur without a clear history of an encounter, especially if the reaction is delayed.
Do Not Miss Diagnoses
- Parotid Gland Tumor: Although rare, a tumor in the parotid gland could cause recurrent swelling in the cheek area. It's crucial to consider this possibility to ensure early detection and treatment if present.
- Lymphoma or Other Malignancies: Certain types of lymphoma or other cancers can cause swelling in the face or cheeks. While these conditions are less common, missing them could have severe consequences.
- Wegener's Granulomatosis (Granulomatosis with Polyangiitis): This is a rare autoimmune disorder that can cause a variety of symptoms, including facial swelling. It's essential to consider this diagnosis due to its potential severity and the need for prompt treatment.
Rare Diagnoses
- Melkersson-Rosenthal Syndrome: A rare neurological disorder characterized by recurrent, often unilateral, facial paralysis or weakness, swelling of the face and lips (usually the upper lip), and the development of folds and furrows in the tongue (fissured tongue). It could be considered in the differential due to the facial swelling component.
- Sarcoidosis: An autoimmune disease that can affect multiple parts of the body, including the skin, and may cause swelling, among other symptoms. Facial swelling could be a manifestation, although it would be part of a broader constellation of symptoms.