Clinical Case: Primary Adhesive Capsulitis in a High-Risk Patient
Patient Presentation
A 52-year-old right-hand-dominant female office worker presents with a 4-month history of progressive right shoulder pain and stiffness that is severely limiting her ability to perform daily activities at work and home.
Chief Complaint
- Insidious onset of deep, aching right shoulder pain that is worse at night, disrupting sleep 1
- Progressive inability to reach overhead or behind her back 1
- Difficulty with basic tasks such as fastening a bra, reaching for items on high shelves, or tucking in her shirt 1
Medical History
- Type 2 diabetes mellitus diagnosed 7 years ago, currently on metformin 1000 mg twice daily with suboptimal glycemic control (HbA1c 8.2%) 2
- Hypertension controlled on lisinopril 20 mg daily 2
- No history of shoulder trauma, surgery, or immobilization 1
- Sedentary occupation with prolonged computer work 3
Physical Examination Findings
Inspection:
- No visible deformity, atrophy, or swelling of the shoulder 1
- Patient holds arm protectively against body 1
Range of Motion (Measured actively and passively):
- Forward elevation: 85° (normal 180°) 1, 4
- External rotation: 15° (normal 90°) - most severely restricted 1, 4
- Internal rotation: Unable to reach posterior superior iliac spine (normally reaches T6-T8) 1
- Abduction: 70° (normal 180°) 1
- Pain throughout range of motion, particularly at end-range 1
- Passive range of motion equally restricted as active range - this is the hallmark finding distinguishing adhesive capsulitis from rotator cuff pathology 1
Strength Testing:
- Difficult to assess secondary to pain and restricted motion, but no focal weakness when tested within available range 1
Special Tests:
Imaging Findings
Plain Radiographs (AP and Lateral Views)
- No significant abnormalities - normal glenohumeral joint space, no fracture, dislocation, or calcifications 1
- Radiographs primarily serve to exclude other pathology such as osteoarthritis, calcific tendinitis, or occult fracture 1
Non-Contrast MRI (1.5T Scanner)
Key diagnostic findings:
- Coracohumeral ligament thickening >3 mm - highly specific for adhesive capsulitis 1, 4
- Axillary recess capsular thickening >4 mm - correlates significantly with restriction in elevation (r = -0.42; p = 0.003) and lateral rotation (r = -0.38; p = 0.008) 4
- Hypersignal in the rotator interval on T2-weighted images indicating inflammation 4
- Obliteration of the subcoracoid fat triangle 4
- No rotator cuff tears, labral pathology, or glenohumeral joint effusion 1
Diagnosis
Primary adhesive capsulitis (frozen shoulder) of the right shoulder in a patient with poorly controlled type 2 diabetes mellitus.
Diagnostic Rationale
- Clinical diagnosis based on characteristic history of insidious onset pain with progressive global restriction of both active and passive shoulder range of motion, particularly external rotation 1
- MRI findings of coracohumeral ligament and capsular thickening provide high specificity for the diagnosis 1, 4
- Critical association with diabetes: This patient has a 38.6% likelihood of having adhesive capsulitis given her diabetic status, which is 2-4 times higher than the general population 5
- Her poor glycemic control (HbA1c 8.2%) further increases risk, as diabetes is believed to play a role in musculoskeletal complications through glycosylation of collagen and microvascular changes 6, 5
Management Plan
Immediate Priorities
1. Optimize Glycemic Control
- Intensify diabetes management immediately - achieving glycemic control can prevent or delay diabetic complications including musculoskeletal manifestations 2, 6
- Target HbA1c <7% through medication adjustment and lifestyle modification 2
- This patient requires urgent diabetes optimization as poor control is associated with worse outcomes in adhesive capsulitis treatment 3
2. Screen for Prediabetes/Undiagnosed Diabetes in Context
- While this patient has known diabetes, the finding of adhesive capsulitis should prompt screening of family members, as 71.5% of patients with adhesive capsulitis have either diabetes or prediabetes 5
- Early diagnosis of diabetes reduces risk of microvascular complications 5
Conservative Treatment (First-Line for 6-12 Weeks)
Pharmacologic Management:
Intra-articular corticosteroid injection combined with physiotherapy provides greater improvement than physiotherapy alone 1
Short-term oral corticosteroids (e.g., prednisone 30 mg daily for 3 weeks with taper) as an alternative or adjunct 1
NSAIDs for pain control (e.g., naproxen 500 mg twice daily with food) 1, 6
Physical Therapy:
- Initiate structured physiotherapy program immediately - this is the cornerstone of treatment 1, 6
- Focus on gentle range-of-motion exercises, stretching, and progressive strengthening 1
- Pendulum exercises, wall walks, and pulley exercises 1
- Avoid aggressive manipulation that may cause pain and protective muscle spasm 1
- 2-3 sessions per week for 6-12 weeks 1
Alternative Therapies:
- Acupuncture may be considered as adjunctive treatment 1
- Hydrodilatation (distension arthrography) can be considered if initial conservative measures fail 1
Surgical Intervention (If Conservative Treatment Fails)
Indications for surgical referral after 6-12 weeks of nonsurgical treatment with minimal improvement: 1
Manipulation under anesthesia (MUA)
Arthroscopic capsular release (preferred over MUA)
Critical Pitfalls to Avoid
- Do not assume spontaneous resolution - recent evidence shows persistent functional limitations if left untreated, challenging the traditional belief of complete resolution within 1-2 years 1
- Do not use corticosteroids without addressing diabetes control - worsening hyperglycemia will compound the underlying pathophysiology 2, 6
- Do not delay physiotherapy - early mobilization is essential to prevent progression 1
- Do not perform aggressive passive stretching early - this may worsen inflammation and pain 1
- Do not miss bilateral involvement - adhesive capsulitis can affect both shoulders, particularly in diabetic patients 6
Blood Pressure Management in Context
- Continue lisinopril 20 mg daily with target BP <130/80 mmHg 2
- ACE inhibitors are preferred in diabetic patients for renal protection 2
- Monitor for orthostatic hypotension, which can be a manifestation of diabetic autonomic neuropathy 2
Cardiovascular Risk Assessment
- Assess 10-year ASCVD risk given her age, diabetes, and hypertension 2
- Check fasting lipid panel 2
- If LDL-C elevated, initiate moderate- to high-intensity statin therapy based on risk stratification 2
- Consider aspirin 75-100 mg daily if 10-year ASCVD risk >10% 2
Screening for Diabetic Complications
Given her 7-year diabetes duration and poor control, perform comprehensive screening: 2
- Annual comprehensive eye examination by ophthalmologist for diabetic retinopathy 2
- Urine albumin-to-creatinine ratio and eGFR for diabetic kidney disease 2
- Foot examination with 10-g monofilament testing for peripheral neuropathy 2
- Assessment for cardiovascular autonomic neuropathy (resting tachycardia, orthostatic hypotension) 2
Follow-Up Schedule
- 2 weeks: Reassess pain control and diabetes management adjustments 1
- 6 weeks: Evaluate response to corticosteroid injection and physiotherapy; consider repeat injection if inadequate response 1
- 12 weeks: If minimal improvement, refer to orthopedic surgery for consideration of manipulation under anesthesia or arthroscopic capsular release 1
- Every 3 months: Monitor HbA1c until target <7% achieved 2
Patient Education
- Explain that adhesive capsulitis is strongly associated with diabetes and that optimizing blood glucose control is essential for treatment success 6, 5, 3
- Set realistic expectations: improvement may take 6-12 months even with treatment 1
- Emphasize importance of daily home exercise program in addition to formal physiotherapy 1
- Counsel on proper diabetes self-management including diet, exercise, and medication adherence 2