What is the most common reason for unsuccessful subclavian (central venous catheter) line placement?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: April 25, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

From the Guidelines

The most common reason for unsuccessful subclavian line placement is anatomical variation leading to difficulty in accessing the subclavian vein, which can be mitigated by using ultrasound guidance as recommended by recent guidelines 1. This typically manifests as an inability to locate or cannulate the vein despite proper positioning and technique. Patient factors that contribute to this challenge include:

  • Obesity
  • Dehydration
  • Hypovolemia
  • Previous vascular injury or thrombosis at the insertion site Technical factors also play a significant role, particularly inadequate positioning of the patient. The optimal position involves placing a rolled towel between the shoulder blades to create a slight extension of the neck and retraction of the shoulders, which helps to make the anatomical landmarks more prominent. Operator inexperience is another major contributor to unsuccessful placement, as the subclavian approach requires significant technical skill and understanding of the relevant anatomy. Using ultrasound guidance can significantly improve success rates by allowing direct visualization of the vein and surrounding structures, helping to avoid arterial puncture and pneumothorax, which are serious complications of this procedure, as supported by guidelines from medical societies 1. However, it's worth noting that while ultrasound guidance offers clear gains in safety and quality for internal jugular vein placement, its benefits for subclavian vein placement are smaller, but still recommended for improving outcomes 1.

From the Research

Unsuccessful Subclavian Line Placement

The most common reasons for unsuccessful subclavian line placement include:

  • Improper site for needle insertion relative to the clavicle
  • Insertion of the needle through the clavicular periosteum
  • Too shallow of a trajectory for the needle
  • Improper or inadequate anatomic landmark identification
  • Aiming the needle too cephalad
  • Inadvertent movement of the needle out of the vein before or during wire placement 2 Other factors associated with failed attempts include:
  • Prior major surgery in the region
  • A body-mass index higher than 30 or lower than 20
  • Previous catheterization 3 Additionally, the number of needle passes is strongly associated with the rates of failure and complications, with the complication rate rising from 4.3 percent with one pass to 24.0 percent with more than two passes 3

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Avoiding common technical errors in subclavian central venous catheter placement.

Journal of the American College of Surgeons, 2009

Research

Complications and failures of subclavian-vein catheterization.

The New England journal of medicine, 1994

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.