Differential Diagnosis for Panniculitis and Joint Pain
- Single most likely diagnosis
- Erythema Nodosum: This condition is characterized by the sudden onset of painful, erythematous nodules on the lower extremities, often associated with joint pain and systemic symptoms. It is a common cause of panniculitis and can be triggered by various factors, including infections, medications, and systemic diseases.
- Other Likely diagnoses
- Lupus Panniculitis: A subtype of lupus erythematosus that affects the subcutaneous fat, causing painful nodules and joint pain. It is often associated with other systemic symptoms of lupus.
- Alpha-1 Antitrypsin Deficiency: A genetic disorder that can cause panniculitis, joint pain, and lung disease. It is an important consideration in patients with a family history of the condition.
- Weber-Christian Disease: A rare inflammatory disorder that affects the subcutaneous fat, causing painful nodules and joint pain. Its exact cause is unknown, but it may be related to an autoimmune process.
- Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
- Infectious Panniculitis: Caused by bacterial, fungal, or parasitic infections, this condition can be life-threatening if not promptly treated. It is essential to consider infectious causes, especially in immunocompromised patients.
- Pancreatic Panniculitis: Associated with pancreatic disease, such as pancreatitis or pancreatic cancer, this condition can cause severe panniculitis and joint pain. It is crucial to evaluate for underlying pancreatic disease.
- Rare diagnoses
- Subcutaneous Fat Necrosis of the Newborn: A rare condition that occurs in newborns, causing panniculitis and joint pain. It is often associated with perinatal distress and hypothermia.
- Post-Steroid Panniculitis: A rare condition that occurs after the sudden withdrawal of corticosteroids, causing panniculitis and joint pain. It is essential to consider this diagnosis in patients with a history of steroid use.