From the Research
Orphenadrine is generally not recommended during breastfeeding due to limited safety data. While there are no documented adverse effects in breastfed infants, orphenadrine can potentially pass into breast milk and may cause drowsiness, dry mouth, or other anticholinergic effects in nursing infants 1. If muscle relaxation is needed during breastfeeding, alternative medications with better safety profiles such as cyclobenzaprine or methocarbamol are preferred.
Key Considerations
- The medication's anticholinergic properties could potentially reduce milk production in some women.
- Short-term use at the lowest effective dose (typically 100 mg twice daily) poses less risk than long-term therapy.
- Always consult with your healthcare provider before taking any medication while breastfeeding to discuss the specific risks and benefits in your situation.
Monitoring and Precautions
- If orphenadrine must be used, monitor the breastfed infant for signs of sedation, feeding difficulties, constipation, or urinary retention.
- A risk-benefit analysis should be performed for each mother under orphenadrine treatment wishing to breastfeed her child, taking into account individual risk factors 2.
Breastfeeding Support
- Interventions to support breastfeeding, including professional support, peer support, and formal education, can change behavior and have a moderate net benefit 3.