From the FDA Drug Label
Nursing Mothers It is not known whether this drug is excreted in human milk Because cyclobenzaprine is closely related to the tricyclic antidepressants, some of which are known to be excreted in human milk, caution should be exercised when cyclobenzaprine hydrochloride is administered to a nursing woman.
The use of Myoflex (cyclobenzaprine) in breastfeeding is not recommended due to the lack of information on whether the drug is excreted in human milk and its relation to tricyclic antidepressants, which are known to be excreted in human milk. Caution should be exercised when considering the use of cyclobenzaprine in nursing women 1.
From the Research
Myoflex (triethanolamine salicylate) is generally not recommended during breastfeeding due to limited safety data. While topical medications typically have minimal systemic absorption, Myoflex contains salicylates which are related to aspirin, and there are concerns about potential transfer into breast milk 2. If pain relief is needed while breastfeeding, safer alternatives include acetaminophen (Tylenol) or ibuprofen (Advil, Motrin), which are considered compatible with breastfeeding 2. For topical pain relief, consider products containing menthol or capsaicin instead.
Some key points to consider when evaluating the safety of Myoflex during breastfeeding include:
- The amount of medication that enters breast milk varies based on the maternal serum concentration and the pharmacologic properties of the medication 2
- Prescribers should use current, accurate resources, such as LactMed, to determine the safety of medications during breastfeeding 2, 3
- Safer alternatives, such as acetaminophen or ibuprofen, should be considered when pain relief is needed during breastfeeding 2
Always consult with your healthcare provider before using any medication while breastfeeding, as they can provide personalized recommendations based on your specific situation, the severity of your pain, and the age of your infant. If you do use Myoflex, minimize absorption by applying it sparingly, avoiding application near the breast area, and washing your hands thoroughly after application to prevent accidental transfer to your baby.