What is Nicotinamide adenine dinucleotide (NAD) and its relation to Coronavirus disease 2019 (COVID-19) treatment?

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Last updated: April 27, 2025View editorial policy

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From the Research

NAD (Nicotinamide Adenine Dinucleotide) is not currently recognized as an established treatment for COVID-19, and patients should rely on proven treatments such as antiviral medications, monoclonal antibodies, and supportive care, as recommended by established medical guidelines. NAD is a coenzyme found in all living cells that plays a crucial role in metabolism, particularly in energy production and cellular repair processes. It exists in two forms: NAD+ (oxidized) and NADH (reduced). While some researchers have hypothesized that NAD+ supplementation might help with COVID-19 by potentially supporting immune function and reducing inflammation, there is insufficient clinical evidence to support its use as a treatment 1, 2, 3, 4, 5.

Current Treatments for COVID-19

The primary treatments for COVID-19 include:

  • Antiviral medications, such as remdesivir, which has been shown to improve survival and disease progression in various patient populations with COVID-19 4, 5
  • Monoclonal antibodies, which have been effective in reducing the risk of disease progression in non-hospitalized patients with mild-to-moderate COVID-19 at high risk of disease progression 1
  • Supportive care, which depends on disease severity and may include oxygen therapy, mechanical ventilation, and other interventions

Importance of Following Established Medical Guidelines

It is essential for patients with COVID-19 to follow established medical guidelines and consult healthcare providers rather than relying on unproven supplements. The use of unproven treatments, such as NAD+ supplementation, may lead to delays in seeking effective treatment and potentially worsen outcomes.

Key Takeaways

  • NAD is not a recognized treatment for COVID-19
  • Proven treatments for COVID-19 include antiviral medications, monoclonal antibodies, and supportive care
  • Patients should follow established medical guidelines and consult healthcare providers rather than relying on unproven supplements
  • The use of remdesivir, in combination with dexamethasone, has been associated with lower mortality risk and improved clinical outcomes in patients hospitalized for COVID-19 4

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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