What is the likely cause of a 10-year-old girl's recent behavioral changes, including poor sleep, nocturnal enuresis, declining academic performance, anxiety, and sadness?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: April 27, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Differential Diagnosis for a 10-year-old Girl with Behavioral Changes

The patient presents with recent onset of behavioral changes, including poor sleep, bedwetting, declining grades, anxiety, and sadness. These symptoms, combined with the family's stressful situation, suggest a multifactorial etiology. Here's a categorized differential diagnosis:

  • Single most likely diagnosis
    • Adjustment Disorder with Mixed Emotional Features: This diagnosis is likely due to the patient's recent behavioral changes and emotional distress in response to her parents' financial difficulties and potential divorce. The sudden onset of symptoms after a significant change in her life supports this diagnosis.
  • Other Likely diagnoses
    • Anxiety Disorder: The patient's anxiety and sadness could be indicative of an anxiety disorder, which may be exacerbated by her home situation.
    • Depressive Disorder: The patient's symptoms of sadness, poor sleep, and declining grades could also suggest a depressive disorder, potentially triggered by her family's stressful situation.
    • Trauma or Stressor-Related Disorder: Although not explicitly stated, the possibility of emotional or psychological trauma related to her father's alcohol use and the parental conflict cannot be ruled out.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
    • Child Abuse or Neglect: It is crucial to consider the possibility of child abuse or neglect, especially given the father's alcohol use and the family's stressful situation. Missing this diagnosis could have severe consequences for the patient's well-being.
    • Substance Abuse: Although less likely in a 10-year-old, substance abuse should be considered, especially if the patient is exposed to her father's alcohol use.
    • Suicidal Ideation: Given the patient's symptoms of depression and anxiety, it is essential to assess for suicidal ideation to ensure her safety.
  • Rare diagnoses
    • Pediatric Bipolar Disorder: Although rare in this age group, pediatric bipolar disorder could present with mood swings, irritability, and changes in sleep patterns.
    • Neurodevelopmental Disorders: Certain neurodevelopmental disorders, such as attention-deficit/hyperactivity disorder (ADHD) or autism spectrum disorder, could contribute to the patient's behavioral changes, although they are less likely given the acute onset of symptoms.
    • Medical Conditions with Psychiatric Symptoms: Rare medical conditions, such as thyroid disorders or sleep apnea, could present with psychiatric symptoms and should be considered in the differential diagnosis.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.