What is causing progressive numbness of the lower lip?

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Differential Diagnosis for Progressive Numbness of the Lower Lip

  • Single most likely diagnosis
    • Trauma or injury to the mental nerve: This is a common cause of numbness in the lower lip, often resulting from dental procedures, facial trauma, or local anesthesia.
  • Other Likely diagnoses
    • Dental problems (e.g., abscess, infection): Infections or abscesses in the teeth or gums can cause numbness or tingling in the lower lip.
    • Nutritional deficiencies (e.g., vitamin B12 deficiency): Deficiencies in certain vitamins, such as vitamin B12, can cause numbness or tingling in the lips and mouth.
    • Multiple sclerosis: This chronic condition can cause numbness or tingling in various parts of the body, including the lower lip.
  • Do Not Miss diagnoses
    • Stroke or transient ischemic attack (TIA): Although less common, numbness in the lower lip can be a symptom of a stroke or TIA, particularly if accompanied by other symptoms such as weakness, difficulty speaking, or vision changes.
    • Lyme disease: In rare cases, Lyme disease can cause numbness or tingling in the face, including the lower lip.
    • Sjögren's syndrome: This autoimmune disorder can cause numbness or tingling in the face, including the lower lip, as well as dry mouth and eyes.
  • Rare diagnoses
    • Sarcoidosis: This rare condition can cause numbness or tingling in the face, including the lower lip, as well as other symptoms such as skin lesions and joint pain.
    • Leprosy: Although extremely rare in most parts of the world, leprosy can cause numbness or tingling in the face, including the lower lip, as well as skin lesions and disfigurement.
    • Trigeminal neuralgia: This rare condition can cause sudden, severe pain or numbness in the face, including the lower lip, often triggered by touch or other stimuli.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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