From the FDA Drug Label
DOSAGE AND ADMINISTRATION: Apply a thin layer of clobetasol propionate gel, cream or ointment to the affected skin areas twice daily and rub in gently and completely. The treatment for dyshidrotic eczema with clobetasol propionate involves applying a thin layer of the gel, cream, or ointment to the affected skin areas twice daily.
- Key points:
- Apply a thin layer to the affected skin areas
- Use twice daily
- Rub in gently and completely
- Treatment should be limited to 2 consecutive weeks
- Amounts greater than 50 g per week should not be used 1
From the Research
Dyshidrotic eczema can be effectively treated with a combination of topical corticosteroids, moisturizers, and trigger avoidance, with dupilumab being a promising option for severe cases, as reported in a 2018 study 2. The treatment of dyshidrotic eczema involves a multifaceted approach, including:
- Topical corticosteroids, such as triamcinolone 0.1% or fluocinonide 0.05% cream, applied twice daily to affected areas for 1-2 weeks 3
- Moisturizers, like petroleum jelly or ceramide-containing creams, applied several times daily, especially after washing hands
- Trigger avoidance, including irritating soaps, frequent hand washing, nickel-containing items, and stress For severe cases, a high-potency corticosteroid like clobetasol 0.05% may be needed, but its use should be limited to 2 weeks to avoid skin thinning 3. Additionally, oral antihistamines, such as cetirizine 10mg daily, can help with itching, and oral corticosteroids, like prednisone, may be prescribed for severe cases that don't respond to topical treatments 4. It's also important to note that dyshidrotic eczema is a chronic condition with periods of flares and remission, and treatment should be tailored to each individual's needs, with a focus on managing symptoms and improving quality of life 5, 6, 4.