From the Research
Iposmia (reduced sense of smell) can be associated with Chronic Fatigue Syndrome (CFS), and addressing the underlying CFS may help improve smell function, with the most recent and highest quality study suggesting that olfactory training with essential oils may be a beneficial treatment approach for post-viral smell dysfunction 1. Treatment of CFS typically involves a multifaceted approach including graded exercise therapy, pacing activities, and cognitive behavioral therapy, which may also have a positive effect on smell function. Some key points to consider in managing both conditions include:
- Graded exercise therapy starting with very gentle activity for 5-10 minutes daily, gradually increasing as tolerated, as shown to be effective in reducing fatigue in CFS patients 2
- Pacing activities throughout the day with scheduled rest periods to avoid exacerbating fatigue
- Cognitive behavioral therapy to manage symptoms and improve coping strategies
- Smell training using essential oils like rose, lemon, clove, and eucalyptus to potentially improve olfactory function, with studies suggesting its efficacy in improving olfactory function in patients with post-viral smell dysfunction 3, 4, 1
- Sleep hygiene practices, including consistent sleep schedules and avoiding caffeine after noon, to help improve both conditions While no medications are specifically approved for CFS, some doctors may prescribe low-dose naltrexone or antidepressants like amitriptyline to manage symptoms, but the evidence for their effectiveness is limited 5. The connection between CFS and iposmia likely involves neuroinflammation and immune dysfunction affecting both energy regulation and sensory processing pathways in the brain. Overall, a comprehensive treatment approach addressing both CFS and iposmia, and incorporating the latest evidence on olfactory training and essential oils, may be the most effective way to manage these conditions and improve quality of life.