From the Research
The rash of erythema infectiosum typically resolves within three weeks without sequelae. The characteristic "slapped cheek" facial rash usually appears first, followed by a lacy, reticular rash on the trunk and limbs that can persist for several weeks. According to the most recent study 1, the rash tends to be more intense on extensor surfaces and may recur intermittently before completely resolving. The diagnosis is mainly clinical, and treatment is usually symptomatic and supportive. In some cases, especially in adults, the rash may recur intermittently for several weeks to months before completely resolving, but this is less common in children. The rash may temporarily worsen with exposure to sunlight, heat, exercise, stress, or bathing, and symptomatic relief can be provided with acetaminophen or ibuprofen for any associated discomfort. Key points to consider include:
- The rash usually resolves spontaneously within three weeks
- The characteristic "slapped cheek" facial rash appears first
- A lacy, reticular rash on the trunk and limbs may persist for several weeks
- The rash may recur intermittently before completely resolving, especially in adults
- Treatment is usually symptomatic and supportive, with acetaminophen or ibuprofen providing relief for associated discomfort, as noted in the study 1.