Differential Diagnosis for Night Sweats
- Single Most Likely Diagnosis
- Tuberculosis (TB): Night sweats are a classic symptom of TB, especially in its active form. The body's immune response to the infection can cause an increase in body temperature, leading to sweating at night.
- Other Likely Diagnoses
- Menopause: Hormonal changes during menopause can lead to hot flashes and night sweats in many women.
- Anxiety and Stress: High levels of stress and anxiety can cause hyperarousal, leading to increased body temperature and sweating at night.
- Hypothyroidism: Although less common, some individuals with hypothyroidism may experience night sweats due to the metabolic changes associated with the condition.
- Medications: Certain medications, such as antidepressants, can cause night sweats as a side effect.
- Do Not Miss Diagnoses
- Lymphoma: Night sweats can be a symptom of lymphoma, particularly Hodgkin's lymphoma. It's crucial to investigate this possibility to ensure timely treatment.
- Infections (e.g., endocarditis, osteomyelitis): Systemic infections can cause night sweats due to the body's inflammatory response.
- HIV/AIDS: Night sweats can be an early symptom of HIV infection, making it essential to consider in the differential diagnosis.
- Rare Diagnoses
- Pheochromocytoma: A rare tumor of the adrenal gland that can cause excessive sweating, including night sweats, due to the excessive production of catecholamines.
- Neurological disorders (e.g., autonomic dysfunction): Certain neurological conditions can affect the body's temperature regulation, leading to night sweats.
- Carcinoid syndrome: A rare condition caused by a neuroendocrine tumor that can produce excessive serotonin, leading to flushing and sweating, including night sweats.