Can patients taking Eliquis (apixaban) be exposed to sunlight?

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Last updated: April 29, 2025View editorial policy

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From the Guidelines

Yes, you can go in the sun while taking Eliquis (apixaban), but it's essential to practice normal sun safety measures. Eliquis does not cause photosensitivity reactions like some other medications do, as it works as an anticoagulant by inhibiting clotting factors and does not interact with skin cells in a way that increases sun sensitivity 1. However, it's crucial to wear sunscreen, protective clothing, and seek shade during peak sun hours. According to the guidelines for phototherapy of mycosis fungoides and Sézary syndrome, broad-spectrum sunscreen with an SPF of at least 30 should be applied anytime you are going outside or sitting in front of window glass 1. Additionally, staying hydrated when outdoors, especially in hot weather, is vital, as dehydration can potentially affect how medications work in your body. If you notice any unusual skin reactions while in the sun, it's likely unrelated to Eliquis, but you should still consult your healthcare provider.

Some key sun safety measures to keep in mind include:

  • Wearing protective clothing and seeking shade during peak sun hours
  • Applying broad-spectrum sunscreen with an SPF of at least 30
  • Staying hydrated, especially in hot weather
  • Avoiding sun tanning or tanning beds, as they can affect the amount of UVA you receive during treatments and increase the risk of skin cancer 1
  • Communicating your use of sunscreen with your healthcare provider, especially if you are undergoing any light treatments 1.

It's also important to note that Eliquis has been shown to be effective in reducing the risk of stroke and systemic embolism in patients with nonvalvular atrial fibrillation, with a lower risk of major bleeding compared to warfarin 1. However, this does not directly relate to sun safety, and the primary concern when going in the sun while taking Eliquis is to practice normal sun safety measures to protect your skin.

From the Research

Eliquis (Apixaban) and Sun Exposure

  • There is no direct evidence in the provided studies regarding the safety of going in the sun while taking Eliquis (apixaban) 2, 3, 4, 5, 6.
  • The studies primarily focus on the comparison of apixaban with other anticoagulants, such as warfarin and rivaroxaban, in terms of bleeding risk and efficacy in preventing stroke and thromboembolic events in patients with atrial fibrillation and/or venous thromboembolism.
  • None of the studies mention sun exposure or photosensitivity as a concern for patients taking apixaban.

Bleeding Risk and Apixaban

  • Apixaban has been shown to have a lower risk of major bleeding compared to warfarin in some studies 4, 5, 6.
  • However, the risk of bleeding is still a concern for patients taking apixaban, particularly those with a history of bleeding or certain comorbidities 6.
  • The studies do not provide information on how sun exposure may affect the bleeding risk in patients taking apixaban.

General Precautions for Patients Taking Apixaban

  • Patients taking apixaban should follow their doctor's instructions and take the medication as prescribed 2, 3, 4, 5, 6.
  • It is essential for patients to discuss any concerns or questions they have with their doctor, including those related to sun exposure and bleeding risk.
  • However, based on the provided studies, there is no specific guidance on sun exposure for patients taking apixaban.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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