From the Guidelines
Bio Life Plasma Center requires potential donors to meet specific laboratory criteria, including testing negative for transmissible diseases such as HIV, hepatitis B and C, and syphilis, as well as having acceptable hemoglobin and protein levels, normal liver function tests, and acceptable lipid profiles, as outlined in the most recent guidelines 1. To ensure the safety of both donors and plasma recipients, the center screens for various health indicators.
- Donors must test negative for HIV, hepatitis B and C, and syphilis, as these diseases can be transmitted through plasma donation 1.
- They must also have acceptable hemoglobin levels, with a minimum of 12.5 g/dL for females and 13.0 g/dL for males, to ensure that donation does not pose a risk to their health.
- Protein levels must be adequate, typically with a total protein of at least 6.0 g/dL, to support overall health and plasma quality.
- Normal liver function tests, including ALT and AST within normal ranges, are required to ensure that the donor's liver is healthy enough for plasma donation.
- Acceptable lipid profiles, with non-fasting triglycerides below 400 mg/dL, help assess the donor's cardiovascular health and the quality of the plasma.
- Vital signs must be within normal ranges: blood pressure below 180/100 mmHg and above 90/50 mmHg, pulse between 50-100 beats per minute, and temperature below 99.6°F, to ensure the donor's overall health and safety during the donation process. These criteria, as supported by the most recent guidelines 1, are crucial for ensuring that plasma donation is safe for the donor and that the collected plasma meets quality standards for medical use. The center typically performs these tests during the initial screening and periodically throughout the donor's history to monitor their health status and maintain the quality of the plasma collected.
From the Research
Criteria for Labs for Bio Life Plasma Center
The criteria for labs for Bio Life Plasma Center are not explicitly stated in the provided studies. However, the studies provide information on the seropositivity of various infections, such as hepatitis B, hepatitis C, syphilis, and HIV, in different populations.
- The studies suggest that the prevalence of these infections varies among different populations, such as blood donors 2, 3, people living with HIV/AIDS 4, antenatal women 5, and individuals with sickle cell disease 6.
- The studies also highlight the importance of screening for these infections in different populations, such as blood donors and antenatal women.
- The criteria for labs for Bio Life Plasma Center may include:
- Screening for hepatitis B, hepatitis C, syphilis, and HIV infections
- Testing for HBsAg, anti-HCV, anti-HIV, and syphilis-specific antibodies
- Use of enzyme-linked immunosorbent assay (ELISA) and other diagnostic tests
- Confirmation of positive results using additional tests, such as neutralization assay and Western blot
- The studies do not provide specific information on the criteria for labs for Bio Life Plasma Center, but they suggest that the center may need to follow similar screening and testing protocols as those used in the studies 2, 4, 3, 5, 6.