What is the significance of a prolonged PR interval of 116 milliseconds in a 31-year-old female?

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Last updated: April 30, 2025View editorial policy

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From the Guidelines

A PR interval of 116 milliseconds in a 31-year-old female is within normal limits and typically requires no specific intervention. According to the most recent guidelines, normal PR intervals range from 120-200 milliseconds, with values slightly below 120ms still considered normal variants in many healthy adults 1. No medication or treatment is necessary for this finding alone. The definition of first-degree atrioventricular block is a PR interval >200 ms, which is not the case here 1.

Some key points to consider:

  • Normal ECG findings in athletes, including increased QRS voltage, incomplete RBBB, early repolarization, and sinus bradycardia, are considered normal variants and do not require further evaluation in asymptomatic athletes with no significant family history 1.
  • The PR interval represents the time taken for electrical impulses to travel from the atria through the AV node to the ventricles, and minor variations below the traditional cutoff are common physiological findings, especially in younger individuals with higher resting heart rates or athletes with increased vagal tone.
  • If the patient is experiencing symptoms such as palpitations, dizziness, or syncope, further evaluation with a 12-lead ECG, Holter monitoring, or referral to a cardiologist may be warranted to rule out other cardiac abnormalities.

In this case, since the PR interval is within normal limits, no specific intervention is required, and routine cardiac follow-up as appropriate for the patient's overall health status and risk factors is recommended.

From the Research

PR Interval of 116msec in a 31-Year-Old Female

The PR interval is a measure of the time it takes for the electrical signal to travel from the atria to the ventricles in the heart. A PR interval of 116msec is considered to be within the normal range, which is typically between 120-200msec [ 2 ]. However, it's essential to consider other factors and symptoms to determine the best course of action.

Potential Causes and Considerations

  • The PR interval can be influenced by various factors, including age, sex, and physical condition [ 3 ].
  • Beta-blockers, such as metoprolol, are commonly used to treat arrhythmias and can affect the PR interval [ 4 ].
  • In some cases, a PR interval of 116msec may not require treatment, but it's crucial to monitor and evaluate other symptoms, such as palpitations or shortness of breath [ 5 ].

Treatment Options

  • Beta-blockers, such as bisoprolol, can be effective in treating supraventricular and ventricular arrhythmias [ 3 ].
  • Metoprolol succinate has been shown to be beneficial in the treatment of heart failure and atrial fibrillation [ 5 ].
  • The use of beta-blockers as anti-arrhythmic agents has been supported by several studies, which have demonstrated a reduction in sudden death and ventricular arrhythmias [ 6 ].

Next Steps

  • Consult with a healthcare professional to determine the best course of action and to rule out any underlying conditions that may be contributing to the PR interval of 116msec.
  • Further evaluation, such as a 24-hour Holter monitoring, may be necessary to assess the heart's rhythm and determine the appropriate treatment [ 2 ].

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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