From the Research
Doxycycline typically begins to work against sinusitis symptoms within 1-2 days, though you may not feel complete relief until 3-5 days after starting treatment. The standard dosage for adults with sinusitis is usually 100 mg twice daily for 5-10 days, depending on the severity of the infection 1. While taking doxycycline, it's essential to take the full course as prescribed, even if symptoms improve earlier. Take the medication with a full glass of water, and remain upright for at least 30 minutes afterward to prevent irritation of the esophagus. For optimal absorption, avoid taking doxycycline with dairy products, antacids, or supplements containing calcium, magnesium, iron, or zinc, as these can reduce the medication's effectiveness. Doxycycline works by inhibiting bacterial protein synthesis, preventing bacteria from multiplying while your immune system clears the infection. Some key points to consider when taking doxycycline for sinusitis include:
- The importance of completing the full course of treatment, even if symptoms improve earlier 1
- The potential for interactions with other medications or supplements, such as dairy products or antacids 2
- The need to stay hydrated and take the medication with a full glass of water to prevent esophageal irritation 3 If your symptoms worsen or don't begin to improve after 3 days, contact your healthcare provider as you may need a different antibiotic or additional treatment 1.