From the FDA Drug Label
KENALOG-40 40 mg per 10 mL Injectable Suspension For intramuscular or intra-articular use only The FDA drug label does not answer the question.
From the Research
For diffuse hives, Kenalog (triamcinolone acetonide) can be administered intramuscularly at a dose of 40-80 mg as a single injection, with the typical adult dose being 60 mg, as supported by general medical knowledge and guidelines 1, 2, 3. The dose may be adjusted based on the severity of symptoms and patient characteristics such as weight and medical history.
- The injection should be given deep into the gluteal muscle using proper sterile technique.
- This steroid injection works by suppressing the immune response that causes hives, providing relief that typically begins within 24-48 hours and may last for 1-4 weeks.
- Patients should be monitored for potential side effects including elevated blood glucose, mood changes, and adrenal suppression. The treatment is generally reserved for severe, widespread hives that haven't responded to antihistamines or other first-line treatments, as outlined in the approach to patients with hives 3. It's essential to note that while effective for acute relief, Kenalog injections are not recommended for long-term or frequent use due to cumulative steroid side effects, and patients should follow up with their healthcare provider to address the underlying cause of their hives and develop a long-term management plan, considering the latest guidelines on managing allergic reactions and anaphylaxis 4.