From the Research
Breastfeeding is associated with a reduced risk of multiple sclerosis (MS) relapses in women with the condition, and women with MS should be encouraged to breastfeed if possible, as exclusive breastfeeding for at least 2-3 months postpartum may significantly decrease relapse risk during this vulnerable period. This protective effect is likely related to the hormonal changes that occur during lactation, particularly elevated prolactin levels and suppressed estrogen, which may have immunomodulatory effects beneficial for MS 1. Additionally, breastfeeding delays the return of menstruation and associated hormonal fluctuations that could trigger disease activity.
Some key points to consider:
- Exclusive breastfeeding has been shown to reduce the risk of early postpartum relapses in MS, with a pooled summary odds ratio of 0.63 (95% CI, 0.45-0.88; P = .006) compared to non-breastfeeding 1.
- The decision to breastfeed should be individualized based on the woman's MS disease activity, personal preferences, and consultation with healthcare providers specializing in MS.
- For women with highly active MS, the benefits of restarting effective disease-modifying therapies (DMTs) may outweigh the benefits of exclusive breastfeeding.
- Some medications like glatiramer acetate, interferon beta, and certain monoclonal antibodies may be compatible with breastfeeding, while others are contraindicated 2.
- Women with MS should discuss their specific situation with their neurologist to determine the best course of action for their individual circumstances.
It is essential to weigh the potential benefits of breastfeeding against the need for disease-modifying therapies, considering factors such as disease activity, relapse history, and personal preferences. A recent study found that exclusive breastfeeding reduced the risk of early postpartum relapses, with an adjusted hazard ratio of 0.37 (p = 0.009) 3. Therefore, breastfeeding should be encouraged in women with MS, unless contraindicated by their specific disease activity or medical history.